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Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.11.066
Abstract: Myeloid differentiation protein 2 (MD2) is an essential molecule which recognizes lipopolysaccharide (LPS), leading to initiation of inflammation through the activation of Toll-like receptor 4 (TLR4) signaling. Caffeic acid phenethyl ester (CAPE) from propolis of…
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Keywords:
caffeic acid;
differentiation protein;
phenethyl ester;
myeloid differentiation ... See more keywords
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Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.09.068
Abstract: Myeloid differentiation primary response protein 88 (MyD88), an essential adapter protein used by toll-like receptors (TLR), is a promising target molecule for the treatment of respiratory inflammatory diseases. Previous studies explored the activities of novel…
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Keywords:
acute lung;
myeloid differentiation;
inflammatory;
amino phenylthiazole ... See more keywords
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Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.08.189
Abstract: Myeloid differentiation factor 88 (MyD88) is an adaptor protein of Toll-like receptor (TLR) signalling pathways that activates the innate immune system. Herein, MyD88 was identified in the economically important freshwater fish Pelteobagrus fulvidraco. The complete…
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Keywords:
polyriboinosinic polyribocytidylic;
differentiation factor;
myeloid differentiation;
polyribocytidylic acid ... See more keywords
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Published in 2020 at "Pharmacological research"
DOI: 10.1016/j.phrs.2020.105239
Abstract: Cardiac inflammation has been involved in many pathological processes in the heart including cardiac hypertrophy, fibrosis, adverse remodeling, and dysfunction. Myeloid differentiation factor 2 (MD2) is a key mediating protein that has been shown to…
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Keywords:
md2;
differentiation factor;
myeloid differentiation;
heart ... See more keywords
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Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006235
Abstract: Aberrations in transcription and epigenetic factors lead to neoplastic transformation such as acute myeloid leukemia (AML), which is characterized by accumulation of hyperproliferative blasts originating from leukemic stem cells. The use of therapeutic agents designed…
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Keywords:
smarcd1 negatively;
negatively regulates;
differentiation leukemic;
regulates myeloid ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22093
Abstract: Active BCR related (ABR) gene deactivates ras-related C3 botulinum toxin substrate 1 (RAC1), which plays an essential role in regulating normal hematopoiesis and in leukemia. BCR gene, closely related to ABR, acts as a tumor…
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Keywords:
abr;
factor;
leukemia;
myeloid differentiation ... See more keywords
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Published in 2021 at "Genes"
DOI: 10.3390/genes12050630
Abstract: Hematopoietic differentiation is a well-orchestrated process by many regulators such as transcription factor and long non-coding RNAs (lncRNAs). However, due to the large number of lncRNAs and the difficulty in determining their roles, the study…
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Keywords:
key lncrnas;
mouse myeloid;
myeloid differentiation;
potential key ... See more keywords