Myeloid‐specific deletion of activating transcription factor 6 alpha increases CD11b+ macrophage subpopulations and aggravates lung fibrosis
Sign Up to like & getrecommendations! Published in 2023 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12637
Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial lung disease of unknown etiology. The accumulation of macrophages is associated with disease pathogenesis. The unfolded protein response (UPR) has been linked to macrophage activation… read more here.
Keywords: specific deletion; fibrosis; myeloid specific; macrophage ... See more keywords
Abstract 16007: Myeloid-specific Deletion in Lipid Phosphate Phosphatase3 (plpp3) Increases Cardiac Inflammation
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DOI: 10.1161/circ.142.suppl_3.16007
Abstract: Introduction and Hypothesis: Acute myocardial infarction (AMI) is the leading cause of morbidity and mortality worldwide. The innate immune response plays a major role in cardiac remodeling after AMI. Lysophosphatidic acid (LPA), produced by autotaxin… read more here.
Keywords: deletion; mice; myeloid specific; plpp3 ... See more keywords
Abstract 70: Targeting Myeloid Specific Neutrophil Integrin α9β1 Improves Stroke Outcome Following Transient Cerebral Ischemia in Comorbid Condition of Hyperlipidemia
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DOI: 10.1161/str.49.suppl_1.70
Abstract: Background and Hypothesis: Neutrophils infiltration following reperfusion is the hallmark of ischemic stroke. Integrin α9β1 is highly expressed on neutrophils, upregulated upon activation, stabiliz... read more here.
Keywords: targeting myeloid; integrin; specific neutrophil; neutrophil integrin ... See more keywords