#1827 Myeloma cast nephropathy: is high cut-off hemodialysis effective?
Sign Up to like & getrecommendations! Published in 2024 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfae069.1540
Abstract: Light-chain cast nephropathy is the result of intra-tubular precipitation of light-chains produced by a multiple myeloma. Treatment often includes high cut-off filters hemodialysis (HCO) with the purpose of purifying these chains until the chemotherapy response… read more here.
Keywords: myeloma cast; renal function; dialysis; cast nephropathy ... See more keywords
Improved Outcomes of Myeloma Cast Nephropathy in Newly Diagnosed Multiple Myeloma With Modern Anti‐Myeloma Therapies
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Haematology"
DOI: 10.1111/ejh.14403
Abstract: Myeloma cast nephropathy (MCN) is a driver of renal failure in newly diagnosed multiple myeloma (NDMM) and has been historically associated with increased early mortality. Since patients with moderate to severe renal insufficiency are typically… read more here.
Keywords: multiple myeloma; newly diagnosed; myeloma cast; diagnosed multiple ... See more keywords
Machine learning uncovers prognostically distinct myeloma cast nephropathy phenotypes not captured by standard risk stratification systems
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-5756
Abstract: BACKGROUND Myeloma cast nephropathy (MCN), a driver of renal failure in 10-15% of newly diagnosed multiple myeloma (NDMM), remains understudied. Current risk classification systems, including the 2025 IMS-IMWG high-risk disease definition [PMID 40489728], may not… read more here.
Keywords: myeloma cast; mcn patients; risk; high risk ... See more keywords