HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1.
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DOI: 10.1158/0008-5472.can-17-0115
Abstract: Disease progression and relapse in multiple myeloma is dependent on the ability of the multiple myeloma plasma cells (PC) to reenter the circulation and disseminate throughout the bone marrow. Increased bone marrow hypoxia is associated… read more here.
Keywords: hif; myeloma; ccr1; multiple myeloma ... See more keywords