FAM213A is linked to prognostic significance in acute myeloid leukemia through regulation of oxidative stress and myelopoiesis
Sign Up to like & getrecommendations! Published in 2020 at "Hematological Oncology"
DOI: 10.1002/hon.2728
Abstract: Accurate prediction of malignancies is important in choosing therapeutic strategies. Although there are many genetic and cytogenetic prognostic factors for acute myeloid leukemia (AML), prognosis is difficult to predict because of the heterogeneity of AML.… read more here.
Keywords: prognostic factors; fam213a; myeloid leukemia; acute myeloid ... See more keywords
Immunopathology of chronic critical illness in sepsis survivors: Role of abnormal myelopoiesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4mr0922-690rr
Abstract: Sepsis remains the single most common cause of mortality and morbidity in hospitalized patients requiring intensive care. Although earlier detection and improved treatment bundles have reduced in‐hospital mortality, long‐term recovery remains dismal. Sepsis survivors who… read more here.
Keywords: sepsis; immunopathology; sepsis survivors; myelopoiesis ... See more keywords
Aryl hydrocarbon receptor (AHR) functions in NAD+ metabolism, myelopoiesis and obesity
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2019.02.021
Abstract: Graphical abstract Figure. No caption available. &NA; Diverse physiologic functions of AHR, a transcription factor discovered in studies of dioxin toxicity, are currently elucidated in many laboratories including chemical and microbial defense, immunity and myelopoiesis.… read more here.
Keywords: hydrocarbon receptor; aryl hydrocarbon; obesity; myelopoiesis ... See more keywords
The interplay between critical transcription factors and microRNAs in the control of normal and malignant myelopoiesis.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.04.010
Abstract: Myelopoiesis is a complex process driven by essential transcription factors, including C/EBPα, PU.1, RUNX1, KLF4 and IRF8. Together, these factors are critical for the control of myeloid progenitor cell expansion and lineage determination in the… read more here.
Keywords: transcription; myelopoiesis; lineage; control ... See more keywords
Disordered haematopoiesis and cardiovascular disease: a focus on myelopoiesis.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical science"
DOI: 10.1042/cs20180111
Abstract: Cardiovascular (CV) diseases (CVD) are primarily caused by atherosclerotic vascular disease. Atherogenesis is mainly driven by recruitment of leucocytes to the arterial wall, where macrophages contribute to both lipid retention as well as the inflammatory… read more here.
Keywords: haematopoiesis; disordered haematopoiesis; disease; cvd ... See more keywords
The role of the microbiota in myelopoiesis during homeostasis and inflammation.
Sign Up to like & getrecommendations! Published in 2023 at "International immunology"
DOI: 10.1093/intimm/dxad002
Abstract: The microbiota engages in the development and maintenance of the host immune system. The microbiota affects not only mucosal tissues where it localizes but also the distal organs. Myeloid cells are essential for host defense… read more here.
Keywords: microbiota myelopoiesis; inflammation; microbiota; myelopoiesis ... See more keywords
Dysregulated myelopoiesis and hematopoietic function following acute physiologic insult
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000395
Abstract: Purpose of review The purpose of this review is to describe recent findings in the context of previous work regarding dysregulated myelopoiesis and hematopoietic function following an acute physiologic insult, focusing on the expansion and… read more here.
Keywords: myelopoiesis; following acute; physiologic insult; function ... See more keywords
Pituitary hormone α-MSH promotes tumor-induced myelopoiesis and immunosuppression
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abj2674
Abstract: The hypothalamic–pituitary (HP) unit can produce various hormones to regulate immune responses, and some of its downstream hormones or effectors are elevated in cancer patients. We show that the HP unit can promote myelopoiesis and… read more here.
Keywords: hormone; msh; hormone msh; myelopoiesis ... See more keywords
Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis
Sign Up to like & getrecommendations! Published in 2020 at "Circulation Research"
DOI: 10.1161/circresaha.120.316653
Abstract: Supplemental Digital Content is available in the text. Rationale: Treatment efficacy for diabetes mellitus is largely determined by assessment of HbA1c (glycated hemoglobin A1c) levels, which poorly reflects direct glucose variation. People with prediabetes and… read more here.
Keywords: transient intermittent; intermittent hyperglycemia; diabetes mellitus; myelopoiesis ... See more keywords
Letter by Jian et al Regarding Article, "Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes Mellitus".
Sign Up to like & getrecommendations! Published in 2021 at "Circulation"
DOI: 10.1161/circulationaha.120.049811
Abstract: January 12, 2021 e5 Wen Jian, MD Lang Li, MD, PhD Chun Gui , MD, PhD To the Editor: We have read with great interest the article published in Circulation by Hoyer et al,1 which… read more here.
Keywords: myelopoiesis; marrow endothelial; bone marrow; endothelial cells ... See more keywords
PU.1 Mimic Synthetic Peptides Selectively Bind with GATA-1 and Allow c-Jun PU.1 Binding to Enhance Myelopoiesis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s303235
Abstract: Background Hematopoietic stem cells' commitment to myelopoiesis builds immunity to prevent infection. This process is controlled through transcription factor, especially Purine rich box 1 (PU.1) protein, which plays a central role in regulating myelopoiesis. The… read more here.
Keywords: peptide loaded; jun; transcription factor; hematopoietic stem ... See more keywords