Burden of chemotherapy‐induced myelosuppression among patients with extensive‐stage small cell lung cancer: A retrospective study from community oncology practices
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DOI: 10.1002/cam4.5738
Abstract: Myelosuppression is a major dose‐limiting complication of chemotherapy for patients with extensive‐stage small cell lung cancer (ES‐SCLC). The objective was to describe the burden of myelosuppression, treatment patterns, and supportive care use among patients with… read more here.
Keywords: oncology; myelosuppression; patients extensive; extensive stage ... See more keywords
Patient Burden and Real-World Management of Chemotherapy-Induced Myelosuppression: Results from an Online Survey of Patients with Solid Tumors
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DOI: 10.1007/s12325-020-01419-6
Abstract: Introduction Chemotherapy-induced myelosuppression (CIM) is one of the most common dose-limiting complications of cancer treatment, and is associated with a range of debilitating symptoms that can significantly impact patients’ quality of life. The purpose of… read more here.
Keywords: chemotherapy; online survey; myelosuppression; treatment ... See more keywords
Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis
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DOI: 10.1016/j.jgr.2019.01.001
Abstract: Background Ginseng (G) and Ligustrum lucidum Ait (LLA) are core traditional Chinese medicines in treating myelosuppression formula. The present study was designed to profile effect of G and LLA herb pair (G-LLA) on myelosuppressed mice.… read more here.
Keywords: bone marrow; herb pair; lla; myelosuppression ... See more keywords
Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression.
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DOI: 10.1021/acsmedchemlett.2c00481
Abstract: Wee1 is a tyrosine kinase that is highly expressed in several cancer types. Wee1 inhibition can lead to suppression of tumor cell proliferation and sensitization of cells to the effects of DNA-damaging agents. AZD1775 is… read more here.
Keywords: selective wee1; antitumor; myelosuppression; inhibitors led ... See more keywords
NUDT15 polymorphism and severe azathioprine‐induced myelosuppression in a Chinese man with pemphigus vulgaris
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Dermatology"
DOI: 10.1111/bjd.15840
Abstract: DEAR EDITOR, Pemphigus vulgaris (PV) is a life-threatening autoimmune mucocutaneous disease with formidable treatment challenges. Since the first report of successful treatment of PV in 1969 with azathioprine (AZA), which was originally used to treat… read more here.
Keywords: pemphigus vulgaris; dermatology; myelosuppression; thiopurine induced ... See more keywords
Autologous Hematopoietic Stem Cell Infusion for Myelosuppression after Bcma-CART Therapy in Relapsed Myeloma Patients
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DOI: 10.1182/blood-2019-128410
Abstract: Abstract Background: The adoption of B cell mature antigen (BCMA) targeted chimeric antigen receptor (CAR) T cells is demonstrating promise prospects in refractory relapsed multiple myeloma (RRMM), however the persistent severe myelosuppression remains a serious… read more here.
Keywords: myelosuppression; infusion; stem cell; cell infusion ... See more keywords
Attenuation of cisplatin induced myelosuppression by methanol extract of Cedrus deodara in Wistar rats
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DOI: 10.1515/jcim-2021-0515
Abstract: Abstract Objective The present study was performed to evaluate the protective effects of methanol extract of Cedrus deodara against cisplatin induced. Methods Myelosuppression in albino Wistar rats. All experimental animals were administered with cisplatin on… read more here.
Keywords: methanol extract; myelosuppression; wistar rats; cisplatin induced ... See more keywords
Exosomal miR-122-5p is Related to the Degree of Myelosuppression Caused by Chemotherapy in Patients with Colorectal Cancer
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DOI: 10.2147/cmar.s332384
Abstract: Purpose As rapidly dividing cells are usually the target of anticancer chemotherapy, it is inevitable that rapidly dividing normal cells become damaged, with myelosuppressive effects being a serious side effect of this therapy. Many recent… read more here.
Keywords: myelosuppression; mir 122; exosomal mir; chemotherapy patients ... See more keywords
Ayurveda-based Botanicals as Therapeutic Adjuvants in Paclitaxel-induced Myelosuppression
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DOI: 10.3389/fphar.2022.835616
Abstract: Chemotherapy-induced myelosuppression is one of the major challenges in cancer treatment. Ayurveda-based immunomodulatory botanicals Asparagus racemosus Willd (AR/Shatavari) and Withania somnifera (L.). Dunal (WS/Ashwagandha) have potential role to manage myelosuppression. We have developed a method… read more here.
Keywords: therapeutic adjuvants; induced myelosuppression; ptx; myelosuppression ... See more keywords
Hematopoietic Effects of Angelica gigas Nakai Extract on Cyclophosphamide-Induced Myelosuppression
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DOI: 10.3390/plants11243476
Abstract: Myelosuppression is a major adverse effect of chemotherapy. With the increasing number of cancer patients worldwide, there is a growing interest in therapeutic approaches that reduce the adverse effects of chemotherapy. Angelica gigas Nakai (AGN)… read more here.
Keywords: induced myelosuppression; angelica gigas; myelosuppression; gigas nakai ... See more keywords
Lurasidone Induced Thrombocytopenia: Is it a Signal of Drug Induced Myelosuppression?
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DOI: 10.4103/ijpsym.ijpsym_374_17
Abstract: The U.S. Food and Drug Administration (FDA) has approved a supplemental new drug application Lurasidone (Latuda, Sunovion Pharmaceuticals), an atypical antipsychotic, for the treatment of schizophrenia in adolescents 13–17 years of age. Lurasidone was previously… read more here.
Keywords: thrombocytopenia signal; myelosuppression; drug; induced thrombocytopenia ... See more keywords