4- Substituted sampangine derivatives: Novel acetylcholinesterase and β-myloid aggregation inhibitors.
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DOI: 10.1016/j.ijbiomac.2017.10.157
Abstract: A series of 4- substituted sampangine derivatives (4-aminoalkylaminosampangine Ar-NH(CH2)nNR1R2) has been designed, synthesized, and tested for their ability to inhibit acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and β-myloid (Aβ) aggregation. The synthetic compounds exhibited high AChE inhibitory… read more here.
Keywords: aggregation; sampangine derivatives; acetylcholinesterase; myloid aggregation ... See more keywords