LPAR5 agonist, Compound-1, treatment ameliorates epithelial cell deficits in MYO5B knockout mice and enteroids
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DOI: 10.1152/physiol.2023.38.s1.5732933
Abstract: Functional loss of a motor protein, Myosin Vb (MYO5B), induces a variety of deficits in intestinal epithelial function and causes a congenital diarrheal disorder, microvillus inclusion disease (MVID). Using the tamoxifen-induced epithelial-specific MYO5B-deficient ( Villin-CreERT2;Myo5bflox/flox)… read more here.
Keywords: compound; myo5b; myo5b deficient; loss ... See more keywords