LAUSR

MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics

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0 Published in 2017 at "Cell Reports"

DOI: 10.1016/j.celrep.2017.05.048

Abstract: Summary APPL1- and RAB5-positive signaling endosomes play a crucial role in the activation of AKT in response to extracellular stimuli. Myosin VI (MYO6) and two of its cargo adaptor proteins, GIPC and TOM1/TOM1L2, localize to… read more here.

Keywords: spatial organization; activation; myo6 regulates; signaling endosomes ... See more keywords