MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion
Sign Up to like & getrecommendations! Published in 2018 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddy054
Abstract: Abstract Congenital myasthenic syndromes (CMS) are a group of rare, inherited disorders characterized by compromised function of the neuromuscular junction, manifesting with fatigable muscle weakness. Mutations in MYO9A were previously identified as causative for CMS… read more here.
Keywords: secretion; agrin; intracellular transport; motor ... See more keywords
S-Nitrosylation of RhoGAP Myosin9A Is Altered in Advanced Diabetic Kidney Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.679518
Abstract: The molecular pathogenesis of diabetic kidney disease progression is complex and remains unresolved. Rho-GAP MYO9A was recently identified as a novel podocyte protein and a candidate gene for monogenic FSGS. Myo9A involvement in diabetic kidney… read more here.
Keywords: nitrosylation; diabetic kidney; myo9a; kidney disease ... See more keywords