Peptide Probes for Plasmodium falciparum MyoA Tail Interacting Protein (MTIP): Exploring the Druggability of the Malaria Parasite Motor Complex
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DOI: 10.1021/acschembio.0c00328
Abstract: Malaria remains an endemic tropical disease, and the emergence of Plasmodium falciparum parasites resistant to current front-line medicines means that new therapeutic targets are required. The Plasmodium glideosome is a multiprotein complex thought to be… read more here.
Keywords: myoa; interacting protein; myoa tail; plasmodium falciparum ... See more keywords
Structural role of essential light chains in the apicomplexan glideosome
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DOI: 10.1038/s42003-020-01283-8
Abstract: Gliding, a type of motility based on an actin-myosin motor, is specific to apicomplexan parasites. Myosin A binds two light chains which further interact with glideosome associated proteins and assemble into the glideosome. The role… read more here.
Keywords: myoa; light; essential light; role ... See more keywords