Lmod3 promotes myoblast differentiation and proliferation via the AKT and ERK pathways
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2020.112297
Abstract: Abstract Mutations in the Lmod3 gene have been identified as a genetic cause of nemaline myopathy. However, the mechanism underlying this disease and the function of Lmod3 remain largely unknown. In this study, we found… read more here.
Keywords: differentiation; myoblast differentiation; proliferation; erk pathways ... See more keywords
miR-455-3p Is Negatively Regulated by Myostatin in Skeletal Muscle and Promotes Myoblast Differentiation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c02474
Abstract: Myostatin (MSTN) is a growth and differentiation factor that regulates proliferation and differentiation of myoblasts, which in turn controls skeletal muscle growth. It may regulate myoblast differentiation by influencing miRNA expression, and the present study… read more here.
Keywords: myoblast differentiation; expression; mir 455; differentiation ... See more keywords
Ten-Eleven Translocation-2 (Tet2) Is Involved in Myogenic Differentiation of Skeletal Myoblast Cells in Vitro
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43539
Abstract: Muscle cell differentiation is a complex process that is principally governed by related myogenic regulatory factors (MRFs). DNA methylation is considered to play an important role on the expression of MRF genes and on muscle… read more here.
Keywords: myoblast differentiation; ten eleven; expression; differentiation ... See more keywords
PGC-1α is associated with Schizothorax prenanti myoblast differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Animal Research"
DOI: 10.1080/09712119.2018.1490650
Abstract: ABSTRACT PGC-1α has been considered as an important mediator of functional capacity of muscle. Our previous study indicated that the mRNA level of PGC-1α increased in muscle during Schizothorax prenanti (S. prenanti) growth. To understand… read more here.
Keywords: myoblast differentiation; prenanti myoblast; schizothorax prenanti; differentiation ... See more keywords
Hsp70 Interacts with Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 To Regulate p38MAPK Stability and Myoblast Differentiation during Skeletal Muscle Regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00211-18
Abstract: The regenerative process of injured muscle is dependent on the fusion and differentiation of myoblasts derived from muscle stem cells. Hsp70 is important for maintaining skeletal muscle homeostasis and regeneration, but the precise cellular mechanism… read more here.
Keywords: hsp70; myoblast differentiation; muscle; activated protein ... See more keywords
Therapeutic Potential of Extracellular Vesicles to Restore Alcohol-mediated Impairment of Myoblast Differentiation
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5734763
Abstract: At-risk alcohol use in people living with HIV (PLWH) and chronic binge alcohol (CBA) administration in simian immunodeficiency virus (SIV)-infected macaques are associated with dysfunctional skeletal muscle mass. Our studies have shown that decreased myomiR-206… read more here.
Keywords: alcohol; physiology; mir 206; differentiation ... See more keywords
N-acetyl cysteine prevents arecoline-inhibited C2C12 myoblast differentiation through ERK1/2 phosphorylation
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272231
Abstract: Arecoline is known to induce reactive oxygen species (ROS). Our previous studies showed that arecoline inhibited myogenic differentiation and acetylcholine receptor cluster formation of C2C12 myoblasts. N-acetyl-cysteine (NAC) is a known ROS scavenger. We hypothesize… read more here.
Keywords: c2c12; inhibited c2c12; acetyl cysteine; differentiation ... See more keywords
Metformin regulates myoblast differentiation through an AMPK-dependent mechanism
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281718
Abstract: This study aims to investigate how metformin (Met) affects muscle tissue by evaluating the drug effects on proliferating, differentiating, and differentiated C2C12 cells. Moreover, we also investigated the role of 5’-adenosine monophosphate-activated protein kinase (AMPK)… read more here.
Keywords: cell; cell cycle; ampk; mechanism ... See more keywords
Regulation of Dystroglycan Gene Expression in Early Myoblast Differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.818701
Abstract: Dystroglycan, a component of the dystrophin-associated glycoprotein complex, connects the extracellular matrix and cytoskeleton to maintain muscle membrane integrity. As such, abnormalities of dystroglycan are linked to different types of muscular dystrophies. In an effort… read more here.
Keywords: differentiation; myoblast differentiation; gene expression; dystroglycan gene ... See more keywords
Multi-Omics Approach to Dissect the Mechanisms of Rexinoid Signaling in Myoblast Differentiation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.746513
Abstract: Stem cells represent a key resource in regenerative medicine, however, there is a critical need for pharmacological modulators to promote efficient conversion of stem cells into a myogenic lineage. We have previously shown that bexarotene,… read more here.
Keywords: rexinoid signaling; multi omics; myoblast differentiation; approach dissect ... See more keywords
TP63 Transcripts Play Opposite Roles in Chicken Skeletal Muscle Differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.01298
Abstract: Tumor protein 63 (TP63) comprises multiple isoforms and plays an important role during embryonic development. It has been shown that TP63 knockdown inhibits myogenic differentiation, but which isoform is involved in the underlying myogenic regulation… read more here.
Keywords: skeletal muscle; myoblast differentiation; chicken skeletal; muscle ... See more keywords