MyD88 promotes myoblast fusion in a cell-autonomous manner
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DOI: 10.1038/s41467-017-01866-w
Abstract: Myoblast fusion is an indispensable step for skeletal muscle development, postnatal growth, and regeneration. Myeloid differentiation primary response gene 88 (MyD88) is an adaptor protein that mediates Toll-like receptors and interleukin-1 receptor signaling. Here we… read more here.
Keywords: skeletal muscle; cell autonomous; fusion; myoblast fusion ... See more keywords
HSP70 drives myoblast fusion during C2C12 myogenic differentiation.
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DOI: 10.1242/bio.053918
Abstract: In response to injury, skeletal muscle stem cells (MuSCs) undergo myogenesis where they become activated, proliferate rapidly, differentiate and undergo fusion to form multinucleated myotubes. Dramatic changes in cell size, shape, metabolism and motility occur… read more here.
Keywords: skeletal muscle; hsp70; differentiation; fusion ... See more keywords
miRNA mediated downregulation of cyclase-associated protein 1 (CAP1) is required for myoblast fusion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.899917
Abstract: Myoblast fusion is essential for the formation, growth, and regeneration of skeletal muscle, but the molecular mechanisms that govern fusion and myofiber formation remain poorly understood. Past studies have shown an important role of the… read more here.
Keywords: fusion; cyclase associated; cap1; myoblast fusion ... See more keywords
Fer1L5, a Dysferlin Homologue Present in Vesicles and Involved in C2C12 Myoblast Fusion and Membrane Repair
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DOI: 10.3390/biology9110386
Abstract: Simple Summary Fer1L5 is a dysferlin and myoferlin homologue and has been implicated in muscle membrane fusion events; myoblast fusion and membrane repair respectively during C2C12 skeletal muscle development. The role of Fer1L5 was analyzed… read more here.
Keywords: fer1l5; membrane repair; membrane; fusion ... See more keywords