Rutin treats myocardial damage caused by pirarubicin via regulating miR‐22‐5p‐regulated RAP1/ERK signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22615
Abstract: Our experiments have previously demonstrated that rutin (RUT) can improve myocardial damage caused by pirarubicin (THP). However, the underlying molecular mechanisms remain uncertain. In this study, we developed an microRNA (miRNA) chip by replicating the… read more here.
Keywords: mir; myocardial damage; rap1 erk; signaling pathway ... See more keywords
Downregulation of miR‐34c‐5p alleviates chronic intermittent hypoxia‐induced myocardial damage by targeting sirtuin 1
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DOI: 10.1002/jbt.23164
Abstract: Numerous microRNAs (miRs) are abnormally expressed in response to hypoxia‐induced myocardial damage. Herein, miR‐34c‐5p as a potential pharmaco‐target was investigated in a mouse model of chronic intermittent hypoxia (CIH)‐induced myocardial damage. A mouse model of… read more here.
Keywords: mir 34c; myocardial damage; antagomir 34c; hypoxia ... See more keywords
RIP1/RIP3/MLKL-mediated necroptosis contributes to vinblastine-induced myocardial damage
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03985-3
Abstract: Vinblastine (VBL) has been considered as a first-line anti-tumor drug for many years. However, vinblastine-caused myocardial damage has been continually reported. The underlying molecular mechanism of the myocardial damage remains unknown. Here, we show that… read more here.
Keywords: myocardial damage; necroptosis; vinblastine induced; damage ... See more keywords
Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.03.037
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The leaves of Artocarpus altilis (Parkinson ex F.A.Zorn, Fosberg) (Moraceae) are used in the management of hypertension; this study assessed the cardio-protective effects of the leaf extract on isoproterenol (ISO) induced myocardial damage… read more here.
Keywords: iso; artocarpus altilis; myocardial damage; aqueous extract ... See more keywords
Marjoram extract prevents ischemia reperfusion-induced myocardial damage and exerts anti-contractile effects in aorta segments of male wistar rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114660
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Marjoram (Origanum majoranaL.) is an herb traditionally used as a medicine in different countries, as Morocco and Iran, because of its beneficial cardiovascular effects. Some studies suggest that these effects are due, at… read more here.
Keywords: aorta segments; myocardial damage; male wistar; marjoram extract ... See more keywords
Comparison of myocardial damage among dogs at different stages of clinical leishmaniasis and dogs with idiopathic chronic kidney disease.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary journal"
DOI: 10.1016/j.tvjl.2016.11.015
Abstract: Canine leishmaniasis (CanL) is a systemic disease caused by the protozoan parasite Leishmania infantum. Myocarditis in CanL has been described previously in CanL by histopathological analysis of post-mortem specimens and by evaluation of cardiac troponin… read more here.
Keywords: myocardial damage; group; disease; dogs idiopathic ... See more keywords
Down-regulated HDAC1 and up-regulated microRNA-124-5p recover myocardial damage of septic mice.
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2034583
Abstract: Studies have revealed the relationship between histone deacetylases (HDACs)/microRNAs (miRNAs) and sepsis, but little has ever investigated the mechanism of HDAC1/miR-124-5p in sepsis. Herein, we studied the impacts of HDAC1/miR-124-5p on myocardial damage of septic… read more here.
Keywords: expression; septic mice; mice; mir 124 ... See more keywords
P6249Markers of early myocardial damage in steinert's disease
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DOI: 10.1093/eurheartj/ehz746.0849
Abstract: Myotonic dystrophy type 1 (DM 1), also known as Steinert's disease (SD), is the most common muscular dystrophy in adults. It is characterized by multisystemic involvement and the cardiac affectation is the second leading cause… read more here.
Keywords: gls; steinert disease; myocardial damage; early myocardial ... See more keywords
P-2181. Cardiac MRI Identifies Heart Disease Risk in Individuals with Hepatitis C Regardless of Myocardial Damage Markers or Fibrosis Stage
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DOI: 10.1093/ofid/ofae631.2335
Abstract: Abstract Background Infection with hepatitis C virus (HCV) increases the risk of extrahepatic manifestations, including cardiovascular disease (CVD). Cardiac magnetic resonance (CMR) remains the gold standard test for non-invasive structural and functional assessment of the… read more here.
Keywords: hcv infected; infected individuals; hcv; myocardial damage ... See more keywords
ESMOLOL PROTECTS AGAINST LPS-INDUCED CARDIAC INJURY VIA THE AMPK/mTOR/ULK1 PATHWAY IN RAT
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DOI: 10.1097/shk.0000000000002071
Abstract: ABSTRACT Aim: The purpose of this study was to investigate the effect of esmolol (ES) on LPS-induced cardiac injury and the possible mechanism. Methods: Sepsis was induced by i.p. injection of LPS (10 mg/kg) in… read more here.
Keywords: damage; mtor; myocardial damage; lps induced ... See more keywords
Soluble uric acid induces myocardial damage through activating the NLRP3 inflammasome
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DOI: 10.1111/jcmm.15523
Abstract: Uric acid crystal is known to activate the NLRP3 inflammasome and to cause tissue damages, which can result in many diseases, such as gout, chronic renal injury and myocardial damage. Meanwhile, soluble uric acid (sUA),… read more here.
Keywords: uric acid; inflammasome; myocardial damage; sua ... See more keywords