Cardiomyopathy in Muscular Dystrophy: When to Treat?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2016.4910
Abstract: Duchenne muscular dystrophy (DMD) is a rare, X-linked condition with progressive muscle weakness and accompanying cardiomyopathy. Cardiovascular magnetic resonance (CMR) has proved particularly useful for monitoring the earliest signs of cardiac involvement in DMD, including… read more here.
Keywords: dmd; fibrosis; cardiology; muscular dystrophy ... See more keywords
LncRNA TUG1 Acts as a Competing Endogenous RNA to Mediate CTGF Expression by Sponging miR-133b in Myocardial Fibrosis after Myocardial Infarction.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology international"
DOI: 10.1002/cbin.11707
Abstract: Myocardial fibrosis is one of the basic causes of many cardiovascular diseases. Noncoding RNAs (ncRNAs), including microRNA (miRNA) and long noncoding RNA (lncRNA), have been reported to play an indispensable role in myocardial fibrosis. The… read more here.
Keywords: mir 133b; myocardial fibrosis; expression; ctgf ... See more keywords
Myocardial fibrosis and MitraClip: Does it even matter?
Sign Up to like & getrecommendations! Published in 2019 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.28311
Abstract: Preprocedural myocardial fibrosis as identified by magnetic resonance imaging correlates with worse outcomes after MitraClip placement. Post‐MitraClip mitral regurgitation gradient >2 or ischemic cardiomyopathy also correlates with worse outcomes. In the literature, other variables are… read more here.
Keywords: mitraclip; myocardial fibrosis; mitraclip even; fibrosis mitraclip ... See more keywords
Myocardial fibrosis in athletes: Additional considerations
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cardiology"
DOI: 10.1002/clc.23466
Abstract: Dear Editor, We would like to thank Martin et al for their interest with our recent review on the current perspective in myocardial fibrosis in athletes and the provided comments. In their letter, the authors… read more here.
Keywords: heart; fibrosis; myocardial fibrosis; pathology ... See more keywords
Diagnostic Value of PICP and PIIINP in Myocardial Fibrosis: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical cardiology"
DOI: 10.1002/clc.23901
Abstract: Myocardial fibrosis is the excessive accumulation of extracellular matrix (ECM) components such as collagen and fibronectin, and its clinical diagnosis is always with limitations. Recently, PICP and PIIINP have been reported by several studies as… read more here.
Keywords: myocardial fibrosis; value picp; picp piiinp; fibrosis ... See more keywords
Apigenin inhibits isoproterenol‐induced myocardial fibrosis and Smad pathway in mice by regulating oxidative stress and miR‐122‐5p/155‐5p expressions
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development Research"
DOI: 10.1002/ddr.21928
Abstract: Apigenin, a flavonoid isolated from Apium graveolens, is an effective natural active ingredient that inhibits transforming growth factor‐β1 (TGF‐β1)‐induced cardiac fibroblasts (CFs) differentiation and collagen synthesis. However, its effects on isoproterenol‐induced myocardial fibrosis in mice… read more here.
Keywords: apigenin; myocardial fibrosis; mir 122; mice ... See more keywords
Mechanosensitive molecular mechanisms of myocardial fibrosis in living myocardial slices
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13832
Abstract: Altered mechanical load in response to injury is a main driver of myocardial interstitial fibrosis. No current in vitro model can precisely modulate mechanical load in a multicellular environment while maintaining physiological behaviour. Living myocardial… read more here.
Keywords: myocardial slices; myocardial fibrosis; molecular mechanisms; mechanosensitive molecular ... See more keywords
Prospective cardiac magnetic resonance imaging survey in myelodysplastic syndrome patients: insights from an Italian network
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Hematology"
DOI: 10.1007/s00277-021-04495-y
Abstract: We prospectively evaluated changes in cardiac and hepatic iron overload (IO) and in morpho-functional cardiac parameters and myocardial fibrosis by magnetic resonance imaging (MRI) in patients with low-risk and intermediate-1-risk myelodysplastic syndromes (MDS). Fifty patients… read more here.
Keywords: iron; magnetic resonance; myocardial fibrosis; resonance imaging ... See more keywords
Clinical aspects of myocardial fibrosis in adults with Ebstein’s anomaly
Sign Up to like & getrecommendations! Published in 2018 at "Heart and Vessels"
DOI: 10.1007/s00380-018-1141-5
Abstract: Heart failure and arrhythmia are common complications in adults with Ebstein’s anomaly. They may result not only from hemodynamic alterations, but also from myocardial fibrosis. Late gadolinium enhancement (LGE) by CMR enables the evaluation of… read more here.
Keywords: fibrosis; clinical aspects; myocardial fibrosis; ebstein anomaly ... See more keywords
Epigenetically modified cardiac mesenchymal stromal cells limit myocardial fibrosis and promote functional recovery in a model of chronic ischemic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2018 at "Basic Research in Cardiology"
DOI: 10.1007/s00395-018-0710-1
Abstract: Preclinical investigations support the concept that donor cells more oriented towards a cardiovascular phenotype favor repair. In light of this philosophy, we previously identified HDAC1 as a mediator of cardiac mesenchymal cell (CMC) cardiomyogenic lineage… read more here.
Keywords: ischemic cardiomyopathy; myocardial fibrosis; chronic ischemic; cmc ... See more keywords
Machine Learning-Based Segmentation of Left Ventricular Myocardial Fibrosis from Magnetic Resonance Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Current Cardiology Reports"
DOI: 10.1007/s11886-020-01321-1
Abstract: Purpose of Review Myocardial fibrosis (MF) arises due to myocardial infarction and numerous cardiac diseases. MF may lead to several heart disorders, such as heart failure, arrhythmias, and ischemia. Cardiac magnetic resonance (CMR) imaging techniques,… read more here.
Keywords: machine learning; segmentation; magnetic resonance; myocardial fibrosis ... See more keywords