Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.057
Abstract: Previous evidences suggested that atorvastatin not only reduced blood lipids but also reduced myocardial hypertrophy and remodeling. And it was reported that C/EBPβ (CCAAT/enhancer-binding protein β) played a pivotal role both in the physiologic and… read more here.
Keywords: ccaat enhancer; atorvastatin; hypertrophy; enhancer binding ... See more keywords
Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1/NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107841
Abstract: BACKGROUND Ginsenoside Rg3 (Rg3), one of the most potent components extracted from the roots of the traditional Chinese herb Panax ginseng, has prominent roles in anti-tumor and anti-inflammation. However, the applications of Rg3 against myocardial… read more here.
Keywords: rg3; hypertrophy; myocardial hypertrophy; nlrp3 inflammasome ... See more keywords
Tranilast prevents doxorubicin-induced myocardial hypertrophy and angiotensin II synthesis in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118984
Abstract: An increase in oxidative stress is an important pathological mechanism of heart injury induced by doxorubicin (DOX). Tranilast is an anti-allergy drug that has been shown to possess good antioxidant activity in previous studies. The… read more here.
Keywords: tranilast; hypertrophy; angiotensin; dox ... See more keywords
PRDX2 in Myocyte Hypertrophy and Survival is Mediated by TLR4 in Acute Infarcted Myocardium
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-06718-7
Abstract: Peroxiredoxin 2 (PRDX2) is an antioxidant and molecular chaperone that can be secreted from tumor cells. But the role of PRDX2 in acute myocardial infarction (AMI) is not clear. In the current study, we demonstrate… read more here.
Keywords: h9c2 cells; prdx2 myocyte; hypertrophy; expression ... See more keywords
lncRNA NBR2 attenuates angiotensin II-induced myocardial hypertrophy through repressing ER stress via activating LKB1/AMPK/Sirt1 pathway
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2062527
Abstract: ABSTRACT Myocardial hypertrophy leads to heart failure (HF), and emerging researchers have illustrated that long noncoding RNAs (lncRNAs) modulate myocardial hypertrophy. Here, we explored the role and mechanism of a novel lncRNA, NBR2, in modulating… read more here.
Keywords: myocardial hypertrophy; hypertrophy; ampk sirt1; lncrna nbr2 ... See more keywords
P3702Aortic stenosis and inappropriate myocardial hypertrophy: is there a difference related to gender?
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0556
Abstract: Degenerative aortic valve presents distinct patterns according to gender. Inappropriate myocardial hypertrophy in response to severe aortic stenosis (AS) and their clinical repercussions is of recent interest. To evaluate the influence of gender on the… read more here.
Keywords: inappropriate myocardial; wall; hypertrophy; myocardial hypertrophy ... See more keywords
MTOR INHIBITOR IMPROVES TESTOSTERONE-INDUCED MYOCARDIAL HYPERTROPHY IN HYPERTENSIVE RATS.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of hypertension"
DOI: 10.1097/01.hjh.0000837504.37769.0e
Abstract: OBJECTIVE Compelling evidence have described the incidence of hypertension and left ventricular hypertrophy (LVH) in postmenopausal women is significantly increased worldwide. Our team's previous research identified that androgen was an underlying factor contributing to increased… read more here.
Keywords: myocardial hypertrophy; day; hypertrophy; inhibitor ... See more keywords
IDENTIFICATION OF A GROSS DELETION MUTATION OF GLA GENE IN A FABRY DISEASE FAMILY CHARACTERIZED BY ATRIAL FIBRILLATION AND MYOCARDIAL HYPERTROPHY
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837768.38890.d1
Abstract: Objective: Fabry disease is a rare X-linked lysosomal storage disease caused by GLA gene mutations, which results in the deficient activity of -galactosidase A. The decreased enzymatic activity consequently leads to abnormal accumulation of the… read more here.
Keywords: myocardial hypertrophy; family; fibrillation myocardial; disease ... See more keywords
Myocardial hypertrophy is improved with berberine treatment via long non‐coding RNA MIAT‐mediated autophagy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmacy and Pharmacology"
DOI: 10.1111/jphp.13170
Abstract: This study aimed to evaluate berberine (BBR) effects on myocardial hypertrophy (MH) and associated mechanisms. read more here.
Keywords: treatment via; hypertrophy; berberine treatment; improved berberine ... See more keywords
Exogenous Hydrogen Sulfide Supplement Attenuates Isoproterenol-Induced Myocardial Hypertrophy in a Sirtuin 3-Dependent Manner
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/9396089
Abstract: Hydrogen sulfide (H2S) is a gasotransmitter with a variety of cardiovascular protective effects. Sirtuin 3 (SIRT3) is closely related to mitochondrial function and oxidative stress. We found that NaHS increased SIRT3 expression in the preventive… read more here.
Keywords: iso; supplement; hypertrophy; iso induced ... See more keywords
Analysis of Therapeutic Targets of A Novel Peptide Athycaltide-1 in the Treatment of Isoproterenol-Induced Pathological Myocardial Hypertrophy
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Therapeutics"
DOI: 10.1155/2022/2715084
Abstract: Myocardial hypertrophy is a pathological feature of many heart diseases. This is a complex process involving all types of cells in the heart and interactions with circulating cells. This study is aimed at identifying the… read more here.
Keywords: myocardial hypertrophy; hypertrophy; peptide athycaltide; analysis ... See more keywords