Short‐term changes in left and right systolic function following ferric carboxymaltose: a substudy of the Myocardial‐IRON trial
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DOI: 10.1002/ehf2.13053
Abstract: The mechanisms underlying the beneficial effect of ferric carboxymaltose (FCM) in patients with heart failure (HF) and iron deficiency (ID) have not been completely characterized. The Myocardial‐IRON trial was a double‐blind, randomized trial that evaluated… read more here.
Keywords: iron trial; changes left; myocardial iron; ferric carboxymaltose ... See more keywords
Left atrial active contractile function parameters assessed by cardiac MR are sensitive to myocardial iron
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DOI: 10.1002/jmri.25396
Abstract: To determine the impact of myocardial iron overload on left atrial (LA) volume and function using MR in patients with systemic iron overload. read more here.
Keywords: active contractile; atrial active; myocardial iron; function ... See more keywords
CMR for myocardial iron overload quantification: calibration curve from the MIOT Network
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DOI: 10.1007/s00330-020-06668-1
Abstract: Objectives R2* cardiac magnetic resonance (CMR) allows the non-invasive measurement of myocardial iron. We calibrated cardiac R2* values against myocardial tissue–measured iron concentration by using a segmental approach and we assessed the iron distribution. Methods… read more here.
Keywords: myocardial iron; approach; iron; iron concentration ... See more keywords
Role of CMR feature-tracking derived left ventricular strain in predicting myocardial iron overload and assessing myocardial contractile dysfunction in patients with thalassemia major
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DOI: 10.1007/s00330-020-07599-7
Abstract: Myocardial iron overload (MIO) in thalassemia major (TM) may cause subclinical left ventricular (LV) dysfunction which manifests with abnormal strain parameters before a decrease in ejection fraction (EF). Early detection of MIO using cardiovascular magnetic… read more here.
Keywords: iron overload; cmr; myocardial iron; strain ... See more keywords
Myocardial iron depletion exacerbates end-stage heart failure by promoting adverse remodeling and worsening mitochondrial function
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DOI: 10.1093/ehjci/ehaa946.1144
Abstract: Heart failure (HF) is highly associated with systemic iron deficiency (ID) yet its association with myocardial iron depletion (MID) remains barely unveiled. Similarly, it has been unclear whether and how MID deteriorates the progression to… read more here.
Keywords: heart; mid; heart failure; myocardial iron ... See more keywords
Cardiac MR images of thalassemia major patients with myocardial iron overload: a data note
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DOI: 10.1186/s13104-021-05733-2
Abstract: Objective Patients with thalassemia major (TM) have the highest mortality rate due to heart failure induced by myocardial iron overload. However, T2* weighted MR imaging is currently a gold standard approach for measuring iron overload.… read more here.
Keywords: thalassemia major; iron overload; myocardial iron; iron ... See more keywords