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   Articles with "myocardial ischaemia" as a keyword



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Knockdown of XIST up‐regulates 263294miR‐340‐5p to relieve myocardial ischaemia–reperfusion injury via inhibiting cyclin D1

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recommendations! Published in 2021 at "ESC Heart Failure"

DOI: 10.1002/ehf2.13766

Abstract: Long non‐coding RNAs (lncRNAs) are known to participate in various human diseases, while the role of X inactive‐specific transcript (XIST) binding microRNA‐340‐5p (miR‐340‐5p) remains seldom studied. We aim to identify the role of the XIST/miR‐340‐5p/cyclin… read more here.

Keywords: xist; ischaemia reperfusion; reperfusion injury; myocardial ischaemia ... See more keywords
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Berberine up‐regulates miR‐340‐5p to protect myocardial ischaemia/reperfusion from HMGB1‐mediated inflammatory injury

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recommendations! Published in 2022 at "ESC Heart Failure"

DOI: 10.1002/ehf2.14235

Abstract: Myocardial ischaemia/reperfusion injury (MIRI) is a major cause of heart failure after myocardial infarction. Berberine (BBR) presents anti‐inflammatory and immunosuppressive properties in many diseases. Our research looked into the therapeutic effects and mechanism of BBR… read more here.

Keywords: ischaemia reperfusion; injury; myocardial ischaemia; berberine ... See more keywords
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Dexmedetomidine protects against myocardial ischaemia/reperfusion-induced renal damage in rats

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recommendations! Published in 2018 at "Egyptian Journal of Anaesthesia"

DOI: 10.1016/j.egja.2017.09.005

Abstract: Abstract Background Myocardial ischaemia/reperfusion (MI/R) may induce renal damage. Our aim was to investigate the effects of dexmedetomidine (DEX) administration at two different timings either before or after ischaemia on renal damage induced by MI/R.… read more here.

Keywords: reperfusion; myocardial ischaemia; renal damage; ischaemia reperfusion ... See more keywords
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Evolution of surgical repair of intraseptal anomalous left coronary artery with myocardial ischaemia.

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recommendations! Published in 2023 at "Cardiology in the young"

DOI: 10.1017/s1047951123000197

Abstract: BACKGROUND Anomalous aortic origin of the left coronary artery with intraseptal course is a rare coronary anomaly associated with an increased risk of myocardial ischaemia. The role and techniques for surgical intervention are evolving, with… read more here.

Keywords: artery; left coronary; myocardial ischaemia; intraseptal anomalous ... See more keywords
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Changes in ventricular depolarisation vectors during exercise caused by regional myocardial ischaemia

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-52869-0

Abstract: Research at the Aga Khan University for several years has been directed to find a reliable, low-cost, portable, non-invasive method for identification of coronary artery disease, its location and extent. A new method has been… read more here.

Keywords: depolarisation; vectors exercise; myocardial ischaemia; magnitude direction ... See more keywords
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Epidermal growth factor protects against myocardial ischaemia reperfusion injury through activating Nrf2 signalling pathway

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recommendations! Published in 2019 at "Free Radical Research"

DOI: 10.1080/10715762.2019.1584399

Abstract: Abstract Alleviating the oxidant stress associated with myocardial ischaemia reperfusion has been demonstrated as a potential therapeutic approach to limit ischaemia reperfusion (I/R)-induced cardiac damage. It is reported that EGFR/erbB2 signalling is an important cardiac… read more here.

Keywords: myocardial ischaemia; ischaemia; ischaemia reperfusion; epidermal growth ... See more keywords
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Baicalin regulates macrophages polarization and alleviates myocardial ischaemia/reperfusion injury via inhibiting JAK/STAT pathway

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recommendations! Published in 2020 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2020.1779318

Abstract: Abstract Context Baicalin is an active compound which demonstrates cardioprotection effects against myocardial ischaemia/reperfusion injury (MI/RI). Objective To investigate how baicalin protects against myocardial injury and to explore its potential mechanism. We hypothesized that baicalin-modulated… read more here.

Keywords: baicalin; myocardial ischaemia; ischaemia reperfusion; reperfusion injury ... See more keywords
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Advances in research on the protective mechanisms of traditional Chinese medicine (TCM) in myocardial ischaemia-reperfusion injury

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recommendations! Published in 2022 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2022.2063342

Abstract: Abstract Context Developing effective drugs to treat myocardial ischaemia-reperfusion (MI/R) injury is imperative. Traditional Chinese medicines (TCMs) have had considerable success in the treatment of cardiovascular diseases. Elucidating the mechanisms by which TCMs improve MI/R… read more here.

Keywords: reperfusion injury; myocardial ischaemia; ischaemia reperfusion; injury ... See more keywords

Patchouli alcohol protects against myocardial ischaemia–reperfusion injury by regulating the Notch1/Hes1 pathway

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recommendations! Published in 2022 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2022.2064881

Abstract: Abstract Context Patchouli alcohol (PA) has protective effects on cerebral ischaemia/reperfusion (I/R) injury, but its efficacy on myocardial ischaemia-reperfusion (MI/R) has yet to be addressed. Objective To examine the therapeutic effect of PA on myocardial… read more here.

Keywords: reperfusion injury; hes1; reperfusion; myocardial ischaemia ... See more keywords
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Shenlian extract attenuates myocardial ischaemia-reperfusion injury via inhibiting M1 macrophage polarization by silencing miR-155

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recommendations! Published in 2022 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2022.2117828

Abstract: Abstract Context Shenlian extract (SL) is a combination of Salvia miltiorrhiza Bge. (Labiatae) and Andrographis paniculata (Burm. F.) Wall. Ex Nees (Acanthaceae) extracts, which promote blood circulation and clear endogenous heat toxins. Myocardial ischaemia-reperfusion injury… read more here.

Keywords: mir 155; macrophage polarization; reperfusion; myocardial ischaemia ... See more keywords
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Reduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids

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recommendations! Published in 2019 at "Cardiovascular Research"

DOI: 10.1093/cvr/cvy136

Abstract: Aims Myocardial ischaemia followed by reperfusion (IR) causes an oxidative burst resulting in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte lipids and their role in cardiac cell death. Our… read more here.

Keywords: death; myocardial ischaemia; infarct size; cell ... See more keywords