The Myocardial Microenvironment Modulates the Biology of Transplanted Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-019-01470-y
Abstract: Purpose The maximal efficacy of cell therapy depends on the survival of stem cells, as well as on the phenotypic and biologic changes that may occur on these cells after transplantation. It has been hypothesized… read more here.
Keywords: myocardial microenvironment; biology; mscs; stem ... See more keywords
Macrophage-targeting gene silencing orchestrates myocardial microenvironment remodeling toward the anti-inflammatory treatment of ischemia-reperfusion (IR) injury
Sign Up to like & getrecommendations! Published in 2022 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2022.01.026
Abstract: Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after infarction and thrombolytic therapy, and it is closely related to the free radical explosion and overwhelming inflammatory responses. Herein, macrophage-targeting nanocomplexes (NCs) are developed… read more here.
Keywords: myocardial microenvironment; macrophage targeting; reperfusion injury; ischemia reperfusion ... See more keywords