Contractile heterogeneity in ventricular myocardium
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26512
Abstract: The transmural heterogeneity of the contractility in ventricular muscle has not been well‐studied. Here, we investigated the calcium transient and sarcomere contraction/relaxation in the endocardial (Endo) and epicardial (Epi) myocytes. Endo and Epi myocytes were… read more here.
Keywords: transient sarcomere; heterogeneity; myocardium; calcium ... See more keywords
Dynamic alteration in myocardium creatine during acute infarction using MR chemical exchange saturation transfer (CEST) imaging.
Sign Up to like & getrecommendations! Published in 2022 at "NMR in biomedicine"
DOI: 10.1002/nbm.4704
Abstract: Creatine (Cr) is an essential metabolite in the creatine kinase reaction that plays a critical role in maintaining normal cardiac function. Chemical exchange saturation transfer (CEST) MRI offers a novel way to map myocardium Cr.… read more here.
Keywords: cest; creatine; chemical exchange; acute infarction ... See more keywords
Isolation and Characterization of Intact Cardiomyocytes from Frozen and Fresh Human Myocardium and Mouse Hearts.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0668-1_15
Abstract: Procurement and characterization of intact human cells are essential for studies in regenerative medicine and translational medical research. The selection of the currently available approaches to isolate intact cells depends on the age of the… read more here.
Keywords: characterization intact; mouse hearts; human myocardium; myocardium ... See more keywords
Crocin Improves Diabetes-Induced Oxidative Stress via Downregulating the Nox-4 in Myocardium of Diabetic Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-73234-9_18
Abstract: BACKGROUND Oxidative stress has a crucial role in the pathophysiology of cardiac dysfunction in the diabetic milieu. Crocin is a natural compound that acts as an antioxidant which could potentially ameliorate oxidative damages in various… read more here.
Keywords: myocardium diabetic; diabetic rats; myocardium; diabetes induced ... See more keywords
Biochemical characterization of the catecholaldehyde reactivity of l-carnosine and its therapeutic potential in human myocardium
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2647-y
Abstract: Oxidative deamination of norepinephrine (NE) and dopamine (DA) by monoamine oxidase (MAO) generates the catecholaldehydes 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL) and 3,4-dihydroxyphenylacetaldehyde (DOPAL), respectively, and H2O2. Catecholaldehydes are highly reactive electrophiles that have been implicated as causal factors… read more here.
Keywords: reactivity carnosine; catecholaldehyde; myocardium; reactivity ... See more keywords
The Role of Extracellular DNA and Histones in Ischaemia-Reperfusion Injury of the Myocardium
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-020-06946-6
Abstract: Despite an increase in the rates of survival in patients suffering myocardial infarction, as yet there is no therapy specifically targeting ischaemia and reperfusion injury of the myocardium. With a greater understanding of immune activation… read more here.
Keywords: dna; myocardium; role; ischaemia reperfusion ... See more keywords
Effects of titanium dioxide nanoparticles on the myocardium of the adult albino rats and the protective role of β-carotene (histological, immunohistochemical and ultrastructural study)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-020-09897-2
Abstract: Titanium dioxide nanoparticles (TiO2 NPs) are the most produced nanomaterials. TiO2 NPs are used as a drug carrier and molecular imaging vehicle in the cardiovascular system. We aimed to study TiO2 NPs effects on the… read more here.
Keywords: adult; titanium dioxide; group; tio2 nps ... See more keywords
Evaluation of Radioiodinated 1,4-Naphthoquinones as Necrosis Avid Agents for Rapid Myocardium Necrosis Imaging
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-017-1089-3
Abstract: PurposeIdentifying necrotic myocardium in ischemic regions is of great importance for risk stratification and clinical decision-making. However, rapid noninvasive imaging of necrotic myocardium is still challenging. This study sought to evaluate the potential of 1,4-naphthoquinones… read more here.
Keywords: necrosis; necrotic myocardium; myocardium; necrosis avidity ... See more keywords
Chronic total occlusion without collateral blood flow does not exclude myocardial viability and subsequent recovery after revascularization
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-018-1273-0
Abstract: Despite significant progress in drug development improvement, mortality in patients with ischemic heart failure remains high, specifically in medically treated patients. In these patients, the left ventricular ejection fraction (LVEF) is important for long-term outcome;… read more here.
Keywords: improvement; cardiology; viability; myocardium ... See more keywords
Potential errors in interpreting hibernation due to FDG scaling?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-019-01953-z
Abstract: Metabolic imaging of the myocardium using positron emission tomography (PET) provides a rational basis to select patients for revascularization by distinguishing between hibernating and infarcted tissues. As in many areas, however, the devil lies in… read more here.
Keywords: potential errors; perfusion; myocardium; glucose metabolism ... See more keywords
Left ventricular mechanical dyssynchrony as a target for therapy in patients with left ventricular aneurysm
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-020-02431-7
Abstract: Left ventricular (LV) mechanical dyssynchrony (MD) represents dyskinetic myocardium or myocardial scar tissue which ‘‘pushes outwards’’ during systole, and has been shown previously to be and independent marker of poor outcome. Dyssynchronous myocardium is deleterious… read more here.
Keywords: mechanical dyssynchrony; ventricular mechanical; cardiology; myocardium ... See more keywords