Ranolazine-Mediated Attenuation of Mechanoelectric Feedback in Atrial Myocyte Monolayers
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DOI: 10.3389/fphys.2020.00922
Abstract: Background Mechanical stretch increases Na+ inflow into myocytes, related to mechanisms including stretch-activated channels or Na+/H+ exchanger activation, involving Ca2+ increase that leads to changes in electrophysiological properties favoring arrhythmia induction. Ranolazine is an antianginal… read more here.
Keywords: ranolazine; stretch; myocyte monolayers; atrial myocyte ... See more keywords