Master control: transcriptional regulation of mammalian Myod
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Muscle Research and Cell Motility"
DOI: 10.1007/s10974-019-09538-6
Abstract: MYOD is a master regulator of the skeletal myogenic program. But what regulates expression of Myod? More than 20 years ago, studies established that Myod expression is largely controlled by just two enhancer regions located within… read more here.
Keywords: master; control; myod; myod expression ... See more keywords
MyoD is a 3D genome structure organizer for muscle cell identity
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27865-6
Abstract: The genome exists as an organized, three-dimensional (3D) dynamic architecture, and each cell type has a unique 3D genome organization that determines its cell identity. An unresolved question is how cell type-specific 3D genome structures… read more here.
Keywords: cell identity; muscle cell; muscle; myod ... See more keywords
Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx773
Abstract: Abstract Our current understanding of cellular transdifferentiation systems is limited. It is oftentimes unknown, at a genome-wide scale, how much transdifferentiated cells differ quantitatively from both the starting cells and the target cells. Focusing on… read more here.
Keywords: transdifferentiation; chromatin; gene expression; myod ... See more keywords
Cis-regulatory determinants of MyoD function
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky388
Abstract: Abstract Muscle-specific transcription factor MyoD orchestrates the myogenic gene expression program by binding to short DNA motifs called E-boxes within myogenic cis-regulatory elements (CREs). Genome-wide analyses of MyoD cistrome by chromatin immnunoprecipitation sequencing shows that… read more here.
Keywords: genome wide; determinants myod; regulatory determinants; myod ... See more keywords
Myotube differentiation in clustered regularly interspaced short palindromic repeat/Cas9-mediated MyoD knockout quail myoblast cells
Sign Up to like & getrecommendations! Published in 2017 at "Asian-Australasian Journal of Animal Sciences"
DOI: 10.5713/ajas.16.0749
Abstract: Objective In the livestock industry, the regulatory mechanisms of muscle proliferation and differentiation can be applied to improve traits such as growth and meat production. We investigated the regulatory pathway of MyoD and its role… read more here.
Keywords: muscle differentiation; myod; differentiation; qm7 ... See more keywords