Abstract 4366989: Pathogenic variants in myoferlin ( MYOF) cause arrhythmogenic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circ.152.suppl_3.4366989
Abstract: Background: Arrhythmogenic cardiomyopathy (ACM) is an inherited disease characterized by fibrofatty ventricular remodeling and arrhythmias. ACM patients are at risk for sudden cardiac death (SCD). Yet, 40% of ACM cases are genetically unexplained. Myoferlin (MYOF)… read more here.
Keywords: arrhythmogenic cardiomyopathy; ca2 handling; myof g1654s; myof ... See more keywords
An Emerging Therapeutic Approach by Targeting Myoferlin (MYOF) for Malignant Tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026620666200618123436
Abstract: Myoferlin (MYOF), as a member of the ferlin family, is a type II transmembrane protein with a single transmembrane domain at the carbon terminus. Studies have shown that MYOF is involved in pivotal physiological functions… read more here.
Keywords: emerging therapeutic; myoferlin myof; therapeutic approach; cancer ... See more keywords