LRRC8A critically regulates myofibroblast phenotypes and fibrotic remodeling following myocardial infarction
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DOI: 10.7150/thno.75200
Abstract: Rationale: The transformation of fibroblasts into activated myofibroblasts is a critical step that results in cardiac fibrosis upon myocardial infarction (MI). Leucine-rich repeat-containing protein-8A (LRRC8A) is a multi-functional protein involved in cell survival, growth, and… read more here.
Keywords: fibrotic remodeling; cardiac fibrosis; lrrc8a; myocardial infarction ... See more keywords