Myofibroblast specific targeting approaches to improve fibrosis treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04825f
Abstract: Fibrosis has been shown to develop in individuals with underlying health conditions, especially chronic inflammatory diseases. Fibrosis is often diagnosed in various organs, including the liver, lungs, kidneys, heart, and skin, and has been described… read more here.
Keywords: collagen angiotensin; myofibroblast specific; specific targeting; treatment ... See more keywords
Myofibroblast-Specific TGF&bgr; Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2018 at "Circulation Research"
DOI: 10.1161/circresaha.118.313089
Abstract: Rationale: Hypertrophic cardiomyopathy occurs with a frequency of about 1 in 500 people. Approximately 30% of those affected carry mutations within the gene encoding cMyBP-C (cardiac myosin binding protein C). Cardiac stress, as well as… read more here.
Keywords: myofibroblast specific; fibrotic response; myofibroblast; mybpc340kda ... See more keywords