Anaplastic lymphoma kinase inhibitor therapy in the treatment of inflammatory myofibroblastic tumors in pediatric patients: Case reports and literature review.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2021.02.004
Abstract: BACKGROUND Inflammatory myofibroblastic tumors (IMTs) are a rare subtype of inflammatory pseudotumor frequently associated with rearrangement of the anaplastic lymphoma kinase (ALK) gene. Their treatment has historically relied on at-times challenging and morbid surgical excision.… read more here.
Keywords: lymphoma kinase; myofibroblastic tumors; literature review; anaplastic lymphoma ... See more keywords
Inflammatory myofibroblastic tumor: an under recognized differential of uterine mesenchymal tumors
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DOI: 10.1136/ijgc-2021-003247
Abstract: Inflammatory myofibroblastic tumors of the uterus are uncommon mesenchymal neoplasms with intermediate malignant potential. Previously classified under 'inflammatory pseudotumors', inflammatory myofibroblastic tumors most commonly involve the lungs and intraabdominal soft tissue. Accurate identification is important… read more here.
Keywords: tumor recognized; recognized differential; myofibroblastic tumors; alk ... See more keywords
Molecular Alterations in Pediatric Fibroblastic/Myofibroblastic Tumors: An Appraisal of a Next Generation Sequencing Assay in a Retrospective Single Centre Study
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DOI: 10.1177/10935266211015558
Abstract: Background Pediatric fibroblastic/myofibroblastic tumors (PFMTs) can be challenging to definitively classify. Large case series or diagnostic updates have not been recently published despite identification of molecular alterations that could improve diagnostic accuracy. Our review of… read more here.
Keywords: myofibroblastic tumors; molecular alterations; pediatric fibroblastic; next generation ... See more keywords
Clinical features analysis of inflammatory myofibroblastic tumors of the retroperitoneal and genitourinary system
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DOI: 10.1186/s12894-025-01963-9
Abstract: To explore the clinical features of inflammatory myofibroblastic tumors (IMT) of the retroperitoneal and genitourinary system. We conducted a retrospective analysis of the clinical data of 23 patients with pathologically confirmed retroperitoneal and urogenital inflammatory… read more here.
Keywords: myofibroblastic tumors; system; inflammatory myofibroblastic; treatment ... See more keywords
Targeted treatment in inflammatory myofibroblastic tumors in children.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.10046
Abstract: 10046 Background: Inflammatory myofibroblastic tumors (IMTs) and epithelioid inflammatory myofibroblastic sarcoma (EIMS)-a variant of IMT, are rare mesenchymal neoplasms in children. Surgical resection has been the mainstay of treatment, however it may cause morbidities due… read more here.
Keywords: myofibroblastic tumors; crizotinib; inflammatory myofibroblastic; treatment ... See more keywords
Ultrasonic Manifestations of Mesenteric Inflammatory Myofibroblastic Tumors in Children
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DOI: 10.3389/fped.2019.00039
Abstract: Objective: To explore the ultrasonic manifestations of mesenteric inflammatory myofibroblastic tumors (IMTs) in children. Methods: Seven patients with mesenteric IMTs were retrospectively analyzed. The ultrasonic manifestations, such as the locations, sizes, morphology, borders, internal echo,… read more here.
Keywords: ultrasonic manifestations; blood flow; myofibroblastic tumors; mesenteric inflammatory ... See more keywords
Inflammatory myofibroblastic tumors in children: a single-center retrospective study of clinical features, management, and outcomes
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2025.1667711
Abstract: Background Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm of intermediate malignant potential. While its clinicopathologic features have been described in adults, comprehensive data in the pediatric population remain limited. Methods We retrospectively reviewed… read more here.
Keywords: myofibroblastic tumors; inflammatory myofibroblastic; center retrospective; single center ... See more keywords
Surgical treatment outcomes of pulmonary inflammatory myofibroblastic tumors
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DOI: 10.4103/atm.atm_119_21
Abstract: BACKGROUND: Pulmonary inflammatory myofibroblastic tumor (PIMT) is an extremely rare disease. The aim of this study was to share the surgical outcomes of these tumors. METHODS: Patients who were operated for pulmonary myofibroblastic tumors between… read more here.
Keywords: treatment outcomes; surgical treatment; inflammatory myofibroblastic; myofibroblastic tumors ... See more keywords