A new hypoglycemic mechanism of catalpol revealed by enhancing MyoD/MyoGâmediated myogenesis
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DOI: 10.1016/j.lfs.2018.08.028
Abstract: Aims: Enhancing myogenesis has been identified as a possible target to improve insulin sensitivity and protect against metabolic diseases. Catalpol, an iridoid glycoside, has been shown to exert a hypoglycaemic effect by improvement of insulin… read more here.
Keywords: mechanism; insulin sensitivity; myogenesis; myog ... See more keywords
Myogenin is required for assembly of the transcription machinery on muscle genes during skeletal muscle differentiation
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DOI: 10.1371/journal.pone.0245618
Abstract: Skeletal muscle gene expression is governed by the myogenic regulatory family (MRF) which includes MyoD (MYOD1) and myogenin (MYOG). MYOD1 and MYOG are known to regulate an overlapping set of muscle genes, but MYOD1 cannot… read more here.
Keywords: muscle; myod1; muscle genes; expression ... See more keywords