Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy
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DOI: 10.1038/s41467-021-26516-0
Abstract: Lack of dystrophin causes muscle degeneration, which is exacerbated by chronic inflammation and reduced regenerative capacity of muscle stem cells in Duchenne Muscular Dystrophy (DMD). To date, glucocorticoids remain the gold standard for the treatment… read more here.
Keywords: myogenic cells; muscle; muscular dystrophy; targets myogenic ... See more keywords
Interleukin-1beta (IL-1β)-induced Notch ligand Jagged1 suppresses mitogenic action of IL-1β on human dystrophic myogenic cells
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DOI: 10.1371/journal.pone.0188821
Abstract: Duchenne muscular dystrophy (DMD) is a severe X-linked recessive muscle disorder caused by mutations in the dystrophin gene. Nonetheless, secondary processes involving perturbation of muscle regeneration probably exacerbate disease progression, resulting in the fatal loss… read more here.
Keywords: myogenic cells; dystrophic myogenic; non dystrophic; dmd myogenic ... See more keywords
Aberrant Caspase Activation in Laminin-α2-Deficient Human Myogenic Cells is Mediated by p53 and Sirtuin Activity
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DOI: 10.3233/jnd-170262
Abstract: Background: Mutations in the LAMA2 gene encoding laminin-α2 cause congenital muscular dystrophy Type 1A (MDC1A), a severe recessive disease with no effective treatment. Previous studies have shown that aberrant activation of caspases and cell death… read more here.
Keywords: caspase activation; aberrant caspase; myogenic cells; activation ... See more keywords
Effect of Serum and Oxygen on the In Vitro Culture of Hanwoo Korean Native Cattle-Derived Skeletal Myogenic Cells Used in Cellular Agriculture
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DOI: 10.3390/foods12071384
Abstract: Skeletal muscle-derived myogenic cells (SKMCs) are novel protein sources capable of replacing animal meat. However, SKMCs have not been commercialized owing to poor productivity and the high cost of in vitro cell culture. Therefore, we… read more here.
Keywords: culture; cell; serum; fbs ... See more keywords