SPSB1-mediated inhibition of TGF-β receptor-II impairs myogenesis in inflammation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.13252
Abstract: BACKGROUND Sepsis-induced intensive care unit-acquired weakness (ICUAW) features profound muscle atrophy and attenuated muscle regeneration related to malfunctioning satellite cells. Transforming growth factor beta (TGF-β) is involved in both processes. We uncovered an increased expression… read more here.
Keywords: spsb1 expression; muscle; expression; differentiation ... See more keywords
(-)-Epigallocatechin-3-gallate stimulates myogenic differentiation through TAZ activation.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.03.049
Abstract: Muscle loss is a typical process of aging. Green tea consumption is known to slow down the progress of aging. Their underlying mechanisms, however, remain largely unknown. In this study, we investigated the effect of… read more here.
Keywords: epigallocatechin gallate; differentiation taz; taz; myogenic differentiation ... See more keywords
Gold and gold-silver alloy nanoparticles enhance the myogenic differentiation of myoblasts through p38 MAPK signaling pathway and promote in vivo skeletal muscle regeneration.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.05.027
Abstract: Under the severe trauma condition, the skeletal muscles regeneration process is inhibited by forming fibrous scar tissues. Understanding the interaction between bioactive nanomaterials and myoblasts perhaps has important effect on the enhanced skeletal muscle tissue… read more here.
Keywords: skeletal muscle; myogenic differentiation; muscle; regeneration ... See more keywords
Muscle-derived TRAIL negatively regulates myogenic differentiation.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112165
Abstract: TNF-related apoptosis-inducing ligand (TRAIL) is known to induce apoptosis in cancer cells, although non-apoptotic functions have also been reported for this cytokine in various cell types. TRAIL and its receptor TRAIL-R2 are expressed in skeletal… read more here.
Keywords: myogenic differentiation; trail; muscle; cell cycle ... See more keywords
Simulated microgravity attenuates myogenic differentiation via epigenetic regulations
Sign Up to like & getrecommendations! Published in 2018 at "NPJ Microgravity"
DOI: 10.1038/s41526-018-0045-0
Abstract: The molecular mechanisms involved in myogenic differentiation are relatively well-known. Myogenic differentiation is regulated by the sequential activation of the basic helix-loop-helix myogenic regulatory transcription factors (MRFs), and biomechanical signals play an important role in… read more here.
Keywords: myogenic differentiation; muscle; simulated microgravity; expression ... See more keywords
Reduced B7-H3 expression by PAX3-FOXO1 knockdown inhibits cellular motility and promotes myogenic differentiation in alveolar rhabdomyosarcoma
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-98322-z
Abstract: B7-H3 (also known as CD276) is associated with aggressive characteristics in various cancers. Meanwhile, in alveolar rhabdomyosarcoma (ARMS), PAX3-FOXO1 fusion protein is associated with increased aggressiveness and poor prognosis. In the present study, we explored… read more here.
Keywords: myogenic differentiation; expression; pax3 foxo1; pax3 ... See more keywords
Myogenic Differentiation Potential of Mesenchymal Stem Cells Derived from Fetal Bovine Bone Marrow
Sign Up to like & getrecommendations! Published in 2018 at "Animal Biotechnology"
DOI: 10.1080/10495398.2016.1276926
Abstract: ABSTRACT The myogenic potential of bovine fetal MSC (bfMSC) derived from bone marrow (BM) remains unknown; despite its potential application for the study of myogenesis and its implications for livestock production. In the present study,… read more here.
Keywords: myogenic differentiation; bovine; bone marrow; bfmsc ... See more keywords
Uterine tumours with myogenic differentiation harbouring SRF::RELA fusions
Sign Up to like & getrecommendations! Published in 2022 at "Histopathology"
DOI: 10.1111/his.14724
Abstract: In 2017, a subset of cellular variants of myofibroma and myopericytoma with a smooth muscle‐like immunophenotype and harbouring recurrent SRF::RELA gene fusions was reported. Although the anatomical distribution was found to be quite broad, no… read more here.
Keywords: rela; differentiation harbouring; uterine tumours; srf rela ... See more keywords
Role of miR-200c in Myogenic Differentiation Impairment via p66Shc: Implication in Skeletal Muscle Regeneration of Dystrophic mdx Mice
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/4814696
Abstract: Duchenne muscular dystrophy (DMD) is a genetic disease associated with mutations of Dystrophin gene that regulate myofiber integrity and muscle degeneration, characterized by oxidative stress increase. We previously published that reactive oxygen species (ROS) induce… read more here.
Keywords: skeletal muscle; myogenic differentiation; muscle; mdx ... See more keywords
Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Stem Cells International"
DOI: 10.1155/2019/5387850
Abstract: Introduction Progenitor cells cultured on biomaterials with optimal physical-topographical properties respond with alignment and differentiation. Stromal cells from connective tissue can adversely differentiate to profibrotic myofibroblasts or favorably to smooth muscle cells (SMC). We hypothesized… read more here.
Keywords: topography; myogenic differentiation; microscopy; directional topography ... See more keywords
Abstract B17: MEK inhibition induces myogenic differentiation in RAS-driven rhabdomyosarcoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.ras18-b17
Abstract: Fusion-negative rhabdomyosarcoma (FN-RMS), which lacks PAX3/7 gene rearrangement, arises from skeletal muscle precursor cells that fail to differentiate despite expression of the myogenic master transcription factor, MYOD1. These tumors frequently harbor mutations in RAS isoforms… read more here.
Keywords: ras driven; differentiation; myogenic differentiation; mek inhibition ... See more keywords