Notch1 and Notch2 Signaling Exclusively but Cooperatively Maintain Fetal Myogenic Progenitors.
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DOI: 10.1093/stmcls/sxac056
Abstract: Myogenic progenitors (MPs) generate myocytes that fuse to form myofibers during skeletal muscle development while maintaining the progenitor pool, which is crucial for generating sufficient muscle. Notch signaling has been known to reserve a population… read more here.
Keywords: notch1 notch2; cooperatively maintain; notch2 signaling; signaling exclusively ... See more keywords
Cell Surface Proteins for Enrichment and In Vitro Characterization of Human Pluripotent Stem Cell-Derived Myogenic Progenitors
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DOI: 10.1155/2022/2735414
Abstract: Human myogenic progenitors can be derived from pluripotent stem cells (PSCs) for use in modeling natural and pathological myogenesis, as well as treating muscle diseases. Transgene-free methods of deriving myogenic progenitors from different PSC lines… read more here.
Keywords: cell surface; stem; derived myogenic; myogenic progenitors ... See more keywords
Assessing and enhancing migration of human myogenic progenitors using directed iPS cell differentiation and advanced tissue modelling
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DOI: 10.15252/emmm.202114526
Abstract: Muscle satellite stem cells (MuSCs) are responsible for skeletal muscle growth and regeneration. Despite their differentiation potential, human MuSCs have limited in vitro expansion and in vivo migration capacity, limiting their use in cell therapies for diseases… read more here.
Keywords: tissue modelling; migration; differentiation; advanced tissue ... See more keywords