Aberrant Myokine Signaling in Congenital Myotonic Dystrophy.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.10.018
Abstract: Myotonic dystrophy types 1 (DM1) and 2 (DM2) are dominantly inherited neuromuscular disorders caused by a toxic gain of function of expanded CUG and CCUG repeats, respectively. Although both disorders are clinically similar, congenital myotonic dystrophy… read more here.
Keywords: myokine signaling; dystrophy; cdm; myotonic dystrophy ... See more keywords
Genetic variation of putative myokine signaling is dominated by biological sex and sex hormones
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.76887
Abstract: Skeletal muscle plays an integral role in coordinating physiological homeostasis, where signaling to other tissues via myokines allows for coordination of complex processes. Here, we aimed to leverage natural genetic correlation structure of gene expression… read more here.
Keywords: metabolic tissues; muscle; myokine signaling; sex ... See more keywords