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   Articles with "myometrium" as a keyword



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Estrogen/estrogen receptor action and the pregnant myometrium

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recommendations! Published in 2020 at "Current Opinion in Physiology"

DOI: 10.1016/j.cophys.2019.10.017

Abstract: Estrogen and estrogen action in the myometrium are necessary for a successful pregnancy. Estrogen is required for both the myometrial hyperplastic phase of gestation as well as the contractile response that leads to parturition at… read more here.

Keywords: estrogen; estrogen estrogen; receptor; estrogen receptor ... See more keywords
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Evaluation of Blood Perfusion in the Myometrium of Women with Symmetric Uterine Anomalies Using Dynamic Contrast-Enhanced MRI.

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recommendations! Published in 2020 at "Journal of Minimally Invasive Gynecology"

DOI: 10.1016/j.jmig.2020.08.391

Abstract: Study Objective The objective of our study is to evaluate functional/dynamic enhanced MRI evaluation of the vascular (capillary) circulation of the myometrium and intrauterine septum in patients with symmetric uterine anomalies. Design Prospective cohort study,… read more here.

Keywords: perfusion; blood perfusion; symmetric uterine; uterine anomalies ... See more keywords
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Maternal body mass index and spontaneous contractility of human myometrium in pregnancy

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recommendations! Published in 2017 at "Journal of Perinatology"

DOI: 10.1038/jp.2016.271

Abstract: Objective:There is controversy as to whether maternal body mass index (BMI) influences the contractility of human myometrium in pregnancy. The aim of this study was to examine spontaneous contractile activity of human pregnant myometrium in… read more here.

Keywords: body mass; bmi; mass index; maternal body ... See more keywords

Racial differences in transcriptomics and reactive oxygen species burden in myometrium and leiomyoma.

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recommendations! Published in 2023 at "Human reproduction"

DOI: 10.1093/humrep/dead020

Abstract: STUDY QUESTION Are there differences in Mediator Complex Subunit 12 mutations (MED12) mutation, transcriptomics, and protein expression in uterine myometrium and leiomyomas of Black and White women? SUMMARY ANSWER RNA sequencing, tissue microarray, and immunohistochemistry… read more here.

Keywords: rna sequencing; myometrium; white women; myometrium leiomyoma ... See more keywords
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Immunological changes associated with adenomyosis: a systematic review.

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recommendations! Published in 2020 at "Human reproduction update"

DOI: 10.1093/humupd/dmaa038

Abstract: BACKGROUND Adenomyosis is a benign gynecological disorder associated with subfertility, pelvic pain and abnormal uterine bleeding that have significant consequences for the health and quality of life of women. Histologically, it is defined as the… read more here.

Keywords: immune; adenomyosis; immunological changes; systematic review ... See more keywords

Effects of the KIR7.1 Blocker VU590 on Spontaneous and Agonist-Induced Contractions of Human Pregnant Myometrium

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recommendations! Published in 2017 at "Reproductive Sciences"

DOI: 10.1177/1933719116687657

Abstract: KIR7.1, an inwardly rectifying K+ channel, plays a critical role in regulating uterine excitability during pregnancy and has been suggested as a potential new target for the treatment of conditions arising from dysfunctional uterine contractility,… read more here.

Keywords: vu590; blocker vu590; induced contractions; vu590 spontaneous ... See more keywords
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The pregnant myometrium is epigenetically activated at contractility-driving gene loci prior to the onset of labor in mice

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recommendations! Published in 2020 at "PLoS Biology"

DOI: 10.1371/journal.pbio.3000710

Abstract: During gestation, uterine smooth muscle cells transition from a state of quiescence to one of contractility, but the molecular mechanisms underlying this transition at a genomic level are not well-known. To better understand these events,… read more here.

Keywords: labor; epigenetically activated; gene; contractility driving ... See more keywords
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Inflammation changes the expression of neuropeptide Y receptors in the pig myometrium and their role in the uterine contractility

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recommendations! Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0236044

Abstract: In the experiment the influence of inflammation on neuropeptide Y (NPY) receptor subtype 1 (Y1Rs) and 2 (Y2Rs) expression pattern in the gilt myometrium and NPY effect alone or with Y1Rs and Y2Rs antagonists on… read more here.

Keywords: sal; endometrium myometrium; group; inflammation ... See more keywords
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The effects of apelin on myometrium contractions in pregnant rats.

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recommendations! Published in 2018 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2018.64.11.13

Abstract: Apelin, which is a new hormone, is secreted especially in the brain by hypothalamus as well as by many other organs like the stomach, fat tissue, and the heart. For apelin, whose possible effects on… read more here.

Keywords: myometrium contractions; significant level; pregnancy; apelin ... See more keywords
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IRF5 is increased in labouring myometrium and regulates pro-labour mediators.

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recommendations! Published in 2018 at "Reproduction"

DOI: 10.1530/rep-18-0140

Abstract: Preterm birth continues to be the leading cause of neonatal mortality and morbidities that can extend into adult life. Few treatment options stem from our incomplete understanding of the mechanisms of human labour and delivery.… read more here.

Keywords: irf5; labour mediators; expression; pro inflammatory ... See more keywords
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Diet-induced vitamin D deficiency triggers inflammation and DNA damage profile in murine myometrium

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recommendations! Published in 2018 at "International Journal of Women's Health"

DOI: 10.2147/ijwh.s163961

Abstract: Background Previously, we reported a significantly higher prevalence of uterine fibroids (UFs) in African American women. This minority group also commonly suffers from vitamin D deficiency. We have demonstrated that 1,25(OH)2D3 attains a fibroid growth… read more here.

Keywords: dna damage; murine myometrium; vitamin deficiency; myometrium ... See more keywords