Moesin and myosin IIA modulate phagolysosomal biogenesis in macrophages.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.12.061
Abstract: Biogenesis of phagolysosomes is central to the elimination of pathogens by macrophages. We previously showed that Src homology region 2 domain-containing phosphatase 1 (SHP-1) participates in the regulation of phagosome maturation. Through proteomics, we identified… read more here.
Keywords: myosin; myosin iia; iia modulate; moesin myosin ... See more keywords
MYH9: Structure, functions and role of non-muscle myosin IIA in human disease.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.04.048
Abstract: The MYH9 gene encodes the heavy chain of non-muscle myosin IIA, a widely expressed cytoplasmic myosin that participates in a variety of processes requiring the generation of intracellular chemomechanical force and translocation of the actin… read more here.
Keywords: myosin iia; non muscle; myosin; muscle myosin ... See more keywords
Inhibition of myosin IIA-actin interaction prevents ischemia/reperfusion induced cardiomyocytes apoptosis through modulating PINK1/Parkin pathway and mitochondrial fission.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.04.079
Abstract: BACKGROUND Mitochondrial fission is the essential mechanisms of myocardial ischemia/reperfusion (MI/R)-induced cardiomyocytes apoptosis. Myosin II plays a key role in fission due to the recruitment and actomyosin constriction at the fission site in U2OS cells.… read more here.
Keywords: myosin; fission; myosin iia; iia actin ... See more keywords
Nanoparticle Spikes Enhance Cellular Uptake via Regulating Myosin IIA Recruitment.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.2c12660
Abstract: Spike-like nanostructures are omnipresent in natural and artificial systems. Although biorecognition of nanostructures to cellular receptors has been indicated as the primary factor for virus infection pathways, how the spiky morphology of DNA-modified nanoparticles affects… read more here.
Keywords: cellular uptake; myosin iia; iia recruitment;
Different contributions of nonmuscle myosin IIA and IIB to the organization of stress fiber subtypes in fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e17-04-0215
Abstract: We demonstrated that myosin IIA and IIB are essential for the formation of transverse arcs and ventral stress fibers, respectively. Furthermore, we illustrated the roles of both isoforms in lamellar flattening and also raised the… read more here.
Keywords: iia iib; myosin iia; contributions nonmuscle; stress ... See more keywords