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   Articles with "myostatin" as a keyword



Electrophoretic Detection of Black Market Myostatin Propeptide.

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recommendations! Published in 2022 at "Drug testing and analysis"

DOI: 10.1002/dta.3398

Abstract: Myostatin propeptide is prohibited according to chapter S4 of the "WADA 2022 List of Prohibited Substances and Methods". So far, no approved myostatin-propeptide pharmaceuticals are available. Nevertheless, myostatin-propeptides can be bought on the black market… read more here.

Keywords: myostatin; detection; black market; myostatin propeptide ... See more keywords

Combinatorial Inhibition of Myostatin and Activin A Improves Femoral Bone Properties in the G610C Mouse Model of Osteogenesis Imperfecta

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recommendations! Published in 2022 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4529

Abstract: Osteogenesis imperfecta (OI) is a collagen‐related bone disorder characterized by fragile osteopenic bone and muscle weakness. We have previously shown that the soluble activin receptor type IIB decoy (sActRIIB) molecule increases muscle mass and improves… read more here.

Keywords: g610c; bone; activin; g610c mice ... See more keywords

The authors reply: Letter on: "Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy" by Zhou et al.

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recommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"

DOI: 10.1002/jcsm.12608

Abstract: We would like to thank the comments from Dr Chen on our paper on ‘Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy’. In this study, we combined the survival… read more here.

Keywords: myostatin; muscle; smn; myostatin inhibition ... See more keywords
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Systemic Intravenous Administration of Antisense Therapeutics for Combinatorial Dystrophin and Myostatin Exon Splice Modulation.

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recommendations! Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8651-4_21

Abstract: Using antisense oligonucleotides (AOs) to reframe mutated dystrophin, a recently developed therapeutic approach for Duchenne muscular dystrophy (DMD) named exon skipping, is considered among the most promising treatments for DMD patients. The development of this… read more here.

Keywords: myostatin; dystrophin myostatin; muscle; administration antisense ... See more keywords

Effects of upper-body, lower-body, or combined resistance training on the ratio of follistatin and myostatin in middle-aged men

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recommendations! Published in 2019 at "European Journal of Applied Physiology"

DOI: 10.1007/s00421-019-04180-z

Abstract: PurposeDue to the mechanistic role of myostatin and follistatin in modulating muscle mass, shifts in the follistatin to myostatin ratio (F:M) may help explain changes in muscular size in response to resistance training (RT). The… read more here.

Keywords: myostatin; follistatin myostatin; training; middle aged ... See more keywords

Changes in Serum Myostatin Levels in Alcoholic Hepatitis Correlate with Improvement in MELD

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recommendations! Published in 2020 at "Digestive Diseases and Sciences"

DOI: 10.1007/s10620-020-06632-5

Abstract: Alcoholic hepatitis (AH) is a serious clinical syndrome often associated with muscle wasting. Myostatin, a member of the transforming growth factor-β superfamily, has been studied in diseases with muscle wasting; however, the role of myostatin… read more here.

Keywords: myostatin; serum myostatin; myostatin levels; meld ... See more keywords
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Genetic Variations and Haplotypic Diversity in the Myostatin Gene of New Zealand Cattle Breeds.

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recommendations! Published in 2020 at "Gene"

DOI: 10.1016/j.gene.2020.144400

Abstract: Myostatin (MSTN) is a circulating factor that is secreted by muscle cells, and that acts upon those cells to inhibit the proliferation of muscle fibres during pre-natal muscle growth. The Polymerase Chain Reaction (PCR) coupled… read more here.

Keywords: intron exon; myostatin; new zealand; gene ... See more keywords

FGF-2 targets sclerostin in bone and myostatin in skeletal muscle to mitigate the deleterious effects of glucocorticoid on musculoskeletal degradation.

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recommendations! Published in 2019 at "Life sciences"

DOI: 10.1016/j.lfs.2019.05.022

Abstract: AIM Myokines are associated with regulation of bone and muscle mass. However, limited information is available regarding the impact of myokines on glucocorticoid (GC) mediated adverse effects on the musculoskeletal system. This study investigates the… read more here.

Keywords: fgf; myostatin; skeletal muscle; muscle ... See more keywords

The genetic diversity analysis in the donkey myostatin gene

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recommendations! Published in 2017 at "Journal of Integrative Agriculture"

DOI: 10.1016/s2095-3119(16)61445-4

Abstract: Abstract Myostatin (MSTN) gene negatively controls skeletal muscle development and growth, variations of which play an important role in the regulation of skeletal muscle growth in mammals. However, study on genetic polymorphism ofMSTN gene in… read more here.

Keywords: ofmstn gene; myostatin; genetic diversity; donkey ... See more keywords

Correlations of serum myostatin and irisin with sarcopenia and osteoporosis in rheumatoid arthritis patients: a cross-sectional study

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-07378-8

Abstract: Myostatin and irisin, the key regulators of muscle metabolism, are myokines secreted by skeletal muscles that significantly influence osteoporosis (OP) and sarcopenia. This study investigated the associations of serum myostatin and irisin levels with sarcopenia… read more here.

Keywords: irisin levels; myostatin irisin; irisin; sarcopenia ... See more keywords

Comprehensive analysis of circRNAs and lncRNAs involvement in the development of skeletal muscle in myostatin-deficient rabbits.

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recommendations! Published in 2025 at "Animal biotechnology"

DOI: 10.1080/10495398.2025.2465624

Abstract: Abstract Myostatin (MSTN) protein, lncRNAs, and circRNAs regulate skeletal muscle growth and development. This work aims to compare the expression patterns of circRNAs and lncRNAs in the gluteus maximus tissue of wild-type (WT) and MSTN… read more here.

Keywords: skeletal muscle; muscle; circrnas lncrnas; mstn ... See more keywords