Electrophoretic Detection of Black Market Myostatin Propeptide.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3398
Abstract: Myostatin propeptide is prohibited according to chapter S4 of the "WADA 2022 List of Prohibited Substances and Methods". So far, no approved myostatin-propeptide pharmaceuticals are available. Nevertheless, myostatin-propeptides can be bought on the black market… read more here.
Keywords: myostatin; detection; black market; myostatin propeptide ... See more keywords
Combinatorial Inhibition of Myostatin and Activin A Improves Femoral Bone Properties in the G610C Mouse Model of Osteogenesis Imperfecta
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4529
Abstract: Osteogenesis imperfecta (OI) is a collagen‐related bone disorder characterized by fragile osteopenic bone and muscle weakness. We have previously shown that the soluble activin receptor type IIB decoy (sActRIIB) molecule increases muscle mass and improves… read more here.
Keywords: g610c; bone; activin; g610c mice ... See more keywords
The authors reply: Letter on: "Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy" by Zhou et al.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12608
Abstract: We would like to thank the comments from Dr Chen on our paper on ‘Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy’. In this study, we combined the survival… read more here.
Keywords: myostatin; muscle; smn; myostatin inhibition ... See more keywords
Systemic Intravenous Administration of Antisense Therapeutics for Combinatorial Dystrophin and Myostatin Exon Splice Modulation.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8651-4_21
Abstract: Using antisense oligonucleotides (AOs) to reframe mutated dystrophin, a recently developed therapeutic approach for Duchenne muscular dystrophy (DMD) named exon skipping, is considered among the most promising treatments for DMD patients. The development of this… read more here.
Keywords: myostatin; dystrophin myostatin; muscle; administration antisense ... See more keywords
Effects of upper-body, lower-body, or combined resistance training on the ratio of follistatin and myostatin in middle-aged men
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-019-04180-z
Abstract: PurposeDue to the mechanistic role of myostatin and follistatin in modulating muscle mass, shifts in the follistatin to myostatin ratio (F:M) may help explain changes in muscular size in response to resistance training (RT). The… read more here.
Keywords: myostatin; follistatin myostatin; training; middle aged ... See more keywords
Changes in Serum Myostatin Levels in Alcoholic Hepatitis Correlate with Improvement in MELD
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06632-5
Abstract: Alcoholic hepatitis (AH) is a serious clinical syndrome often associated with muscle wasting. Myostatin, a member of the transforming growth factor-β superfamily, has been studied in diseases with muscle wasting; however, the role of myostatin… read more here.
Keywords: myostatin; serum myostatin; myostatin levels; meld ... See more keywords
Genetic Variations and Haplotypic Diversity in the Myostatin Gene of New Zealand Cattle Breeds.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144400
Abstract: Myostatin (MSTN) is a circulating factor that is secreted by muscle cells, and that acts upon those cells to inhibit the proliferation of muscle fibres during pre-natal muscle growth. The Polymerase Chain Reaction (PCR) coupled… read more here.
Keywords: intron exon; myostatin; new zealand; gene ... See more keywords
FGF-2 targets sclerostin in bone and myostatin in skeletal muscle to mitigate the deleterious effects of glucocorticoid on musculoskeletal degradation.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.05.022
Abstract: AIM Myokines are associated with regulation of bone and muscle mass. However, limited information is available regarding the impact of myokines on glucocorticoid (GC) mediated adverse effects on the musculoskeletal system. This study investigates the… read more here.
Keywords: fgf; myostatin; skeletal muscle; muscle ... See more keywords
The genetic diversity analysis in the donkey myostatin gene
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Integrative Agriculture"
DOI: 10.1016/s2095-3119(16)61445-4
Abstract: Abstract Myostatin (MSTN) gene negatively controls skeletal muscle development and growth, variations of which play an important role in the regulation of skeletal muscle growth in mammals. However, study on genetic polymorphism ofMSTN gene in… read more here.
Keywords: ofmstn gene; myostatin; genetic diversity; donkey ... See more keywords
Skeletal Muscle Anti-Atrophic Effects of Leucine Involve Myostatin Inhibition.
Sign Up to like & getrecommendations! Published in 2020 at "DNA and cell biology"
DOI: 10.1089/dna.2020.5423
Abstract: Lack of mechanical load leads to skeletal muscle atrophy, and one major underlying mechanism involves the myostatin pathway that negatively regulates protein synthesis and also activates Atrogin-1/MAFbx and MuRF1 genes. In hindlimb immobilization, leucine was… read more here.
Keywords: skeletal muscle; myostatin; supplementation; immobilization ... See more keywords
SP567ASSOCIATION BETWEEN AGE AND CHANGES IN HEART RATE VARIABILITY AFTER HEMODIALYSIS IN PATIENTS WITH DIABETES
Sign Up to like & getrecommendations! Published in 2018 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfy104.sp567
Abstract: RESULTS: Our study included 37 hemodialysis patients and 34 peritoneal dialysis (PD) patients with a median age of 59.0 years and a median myostatin level of 4991.4 pg/mL. Patients with low myostatin levels were older… read more here.
Keywords: myostatin; age; myostatin levels; aac scores ... See more keywords