Myostatin inhibitory peptides in sports drug testing.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3473
Abstract: Across species, skeletal muscle mass is negatively regulated by the TGF-β cytokine myostatin (MSTN). Inhibitors of this growth factor and its signaling pathways are therefore not only promising therapeutics for muscular diseases but also potential… read more here.
Keywords: sports drug; myostatin inhibitory; peptides sports; drug ... See more keywords
Chain-Shortened Myostatin Inhibitory Peptides Improve Grip Strength in Mice.
Sign Up to like & getrecommendations! Published in 2019 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.9b00174
Abstract: Inhibition of myostatin is a promising strategy for treatment of muscle atrophic disorders. We had already identified a 23-mer peptide (1) as a synthetic myostatin inhibitor, and structure-activity relationship studies with 1 afforded a potent… read more here.
Keywords: grip strength; myostatin inhibitory; chain shortened;