Human myotubularin-related protein 9 regulates ER-to-golgi trafficking and modulates WNT3A secretion.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2019.111709
Abstract: Regulation of phosphatidylinositol phosphates plays a crucial role in signal transduction, membrane trafficking or autophagy. Members of the myotubularin family of lipid phosphatases contribute to phosphoinositide metabolism by counteracting the activity of phosphoinositide kinases. The… read more here.
Keywords: protein; myotubularin related; secretion; protein regulates ... See more keywords
Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling
Sign Up to like & getrecommendations! Published in 2019 at "Cell Cycle"
DOI: 10.1080/15384101.2019.1661174
Abstract: ABSTRACT Myotubularin related protein 7 (MTMR7), a key member of the MTMR family, depicts phosphatase activity and is involved in myogenesis and tumor growth. We have previously identified MTMR7 in the proteomic profile of mouse… read more here.
Keywords: myotubularin related; akt signaling; pi3k akt; related protein ... See more keywords
Abstract B031: Inhibition of mutant RAS via myotubularin related protein 7-mimicking peptide
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.ras23-b031
Abstract: The coiled coil domain of Myotubularin Related Protein 7 (MTMR7) and a peptide of the same sequence (M7CC) have been shown to have an anti-cancer effect via direct interaction with PPARĪ³ (Weidner et al. 2020).… read more here.
Keywords: related protein; myotubularin related; mutant ras; ras ... See more keywords