Myricetin‐induced oxidative stress suppresses murine T lymphocyte activation
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biology International"
DOI: 10.1002/cbin.10977
Abstract: A number of polyphenolic compounds present in fruits and vegetables have the capacity to modulate immune responses; however, the impact of the common plant‐derived flavonoid myricetin on T lymphocyte function has not been investigated. We… read more here.
Keywords: lymphocyte activation; induced oxidative; cell; myricetin ... See more keywords
Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7427
Abstract: Most antiangiogenic inhibitors targeting endothelium‐dependent vessels cannot inhibit tumor growth but promote tumor invasion and metastasis in some patients. Vasculogenic mimicry (VM) employs mechanisms that differ from those used to construct endothelium‐dependent vessels. Inhibiting VM… read more here.
Keywords: hepatocellular carcinoma; myricetin; vasculogenic mimicry; invasion ... See more keywords
Myricetin protects cardiomyocytes from LPS-induced injury
Sign Up to like & getrecommendations! Published in 2017 at "Herz"
DOI: 10.1007/s00059-017-4556-3
Abstract: BackgroundSepsis-induced cardiomyopathy is a well-known cause of mortality. Recent evidence has highlighted the important role of myricetin in anti-inflammation and anti-oxidative stress. However, little is known about its effect on endotoxin-induced cardiomyopathy. We examined the effect… read more here.
Keywords: von; die; tnf alpha; expression ... See more keywords
Myricetin: versatile plant based flavonoid for cancer treatment by inducing cell cycle arrest and ROS–reliant mitochondria-facilitated apoptosis in A549 lung cancer cells and in silico prediction
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03885-6
Abstract: Myricetin is categorized under the secondary metabolite flavonoid which includes a diverse range of consumable plant parts, and it has a potential against several classes of cancer including cancers and tumors. In the present study,… read more here.
Keywords: a549; lung cancer; cancer; cell ... See more keywords
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114097
Abstract: Idiopathic pulmonary fibrosis is a progressive-fibrosing lung disease with high mortality and limited therapy, which characterized by myofibroblasts proliferation and extracellular matrix deposition. Myricetin, a natural flavonoid, has been shown to possess a variety of… read more here.
Keywords: hsp90; induced pulmonary; pulmonary fibrosis; tgf signaling ... See more keywords
Insights into the aggregation mechanism of Aβ(25-40).
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2016.11.003
Abstract: The hydrophobic fragment of the Alzheimer's related β-amyloid (Aβ) peptide, Aβ(25-40), aggregates and forms insoluble amyloid fibrils at a rate similar to the full-length peptide. In order to gain insight into the fibrillization of Aβ(25-40)… read more here.
Keywords: aggregation; peptide; i32a peptide; myricetin ... See more keywords
Myricetin suppresses invasion and promotes cell death in human placental choriocarcinoma cells through induction of oxidative stress.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.04.014
Abstract: Myricetin is a bioactive compound found in a variety of vegetables and fruits, and its anti-cancer effects are well known. In this study, we confirmed that myricetin reduced proliferation of two choriocarcinoma cell lines (JAR… read more here.
Keywords: human placental; choriocarcinoma cells; myricetin; jar jeg ... See more keywords
Myricetin supplementation decreases hepatic lipid synthesis and inflammation by modulating gut microbiota.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109641
Abstract: The relationship between poor in vivo bioavailability and effective pharmacological activity are not yet fully clarified for many flavonoids. The analysis of flavonoids-induced alterations in the gut microbiota represents a promising approach to provide useful clues… read more here.
Keywords: myricetin; hepatic lipid; gut microbiota; myricetin supplementation ... See more keywords
Structure and functional properties of active packaging films prepared by incorporating different flavonols into chitosan based matrix.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.09.209
Abstract: Kaempferol, quercetin and myricetin are typical flavonols that feature different number of hydroxyl substituents at B-ring. In this study, kaempferol, quercetin and myricetin were individually mixed with chitosan (CS) based film matrix to develop active… read more here.
Keywords: functional properties; active packaging; chitosan based; packaging films ... See more keywords
Myricetin prevents dopaminergic neurons from undergoing neuroinflammation-mediated degeneration in a lipopolysaccharide-induced Parkinson’s disease model
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2018.04.018
Abstract: Abstract Myricetin, one of the lipophenolic compounds present in red wine, has been reported to pass through blood–brain barriers and reduce dopaminergic neuron degeneration, but the mechanism remains unclear. We thoroughly investigated the underlying mechanisms… read more here.
Keywords: prevents dopaminergic; myricetin prevents; parkinson disease; dopaminergic neurons ... See more keywords
Myricetin exerts its antiviral activity against infectious bronchitis virus by inhibiting the deubiquitinating activity of papain-like protease.
Sign Up to like & getrecommendations! Published in 2021 at "Poultry science"
DOI: 10.1016/j.psj.2021.101626
Abstract: Infectious bronchitis virus (IBV) is a causative agent that causes severe economic losses in the poultry industry worldwide. Papain-like protease (PLpro) is a nonstructural protein encoded by IBV. It has deubiquitinating enzyme activity, which can… read more here.
Keywords: infectious bronchitis; inhibiting deubiquitinating; deubiquitinating activity; myricetin ... See more keywords