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Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14565
Abstract: Motile cells have developed a large array of molecular machineries to actively change their direction of movement in response to spatial cues from their environment. In this process, small GTPases act as molecular switches and…
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Keywords:
ras like;
motility;
myxococcus xanthus;
xanthus ... See more keywords
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Published in 2022 at "Biomolecular NMR assignments"
DOI: 10.1007/s12104-022-10083-6
Abstract: Bacterial cell motility is essential for a range of physiological phenomena such as nutrient sensing, predation, biofilm formation and pathogenesis. One of the most intriguing motilities is bacterial gliding, which is defined as the ability…
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Keywords:
myxococcus xanthus;
domains gltj;
cytoplasmic domains;
15n chemical ... See more keywords
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Published in 2019 at "Journal of Microbiology"
DOI: 10.1007/s12275-019-8683-9
Abstract: Myxococcus xanthus, a myxobacterium, displays phase variation between yellow phase and tan phase. We found that deletion of the encA gene encoding encapsulin and the encF gene encoding a metalloprotease causes formation of tan colonies…
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Keywords:
tan phase;
phase;
myxococcus xanthus;
enca encf ... See more keywords
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Published in 2020 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2020.02.005
Abstract: Myxococcus xanthus DK1622 is known as a proficient producer of different kinds of secondary metabolites (SM) with various biological activities, including myxovirescin A, myxalamide A, myxochromide A and DKxanthene. Low production of SM in the…
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Keywords:
protein;
production;
myxococcus xanthus;
xanthus dk1622 ... See more keywords
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Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c02374
Abstract: The alkaloid physostigmine is an approved anticholinergic drug and an important lead structure for the development of novel therapeutics. Using a complementary approach that merged chemical synthesis with pathway refactoring, we produced a series of…
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Keywords:
myxococcus xanthus;
physostigmines myxococcus;
mutasynthesis physostigmines;
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Published in 2018 at "ACS chemical biology"
DOI: 10.1021/acschembio.7b00816
Abstract: The fascinating ability of myxobacteria to form multicellular spore filled fruiting bodies under starvation conditions was widely studied as a model for cooperative microbial behavior. The potential of a life cycle induced change of secondary…
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Keywords:
class;
myxococcus xanthus;
xanthus dk1622;
compound class ... See more keywords
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Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02015-z
Abstract: In bacteria, homologs of actin, tubulin, and intermediate filament proteins often act in concert with bacteria-specific scaffolding proteins to ensure the proper arrangement of cellular components. Among the bacteria-specific factors are the bactofilins, a widespread…
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Keywords:
parabs chromosome;
myxococcus xanthus;
segregation system;
chromosome segregation ... See more keywords
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Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15628-8
Abstract: Cyclic di-GMP (c-di-GMP) is a second messenger that modulates multiple responses to environmental and cellular signals in bacteria. Here we identify CdbA, a DNA-binding protein of the ribbon-helix-helix family that binds c-di-GMP in Myxococcus xanthus.…
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Keywords:
dna;
myxococcus xanthus;
organization segregation;
gmp ... See more keywords
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Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18803-z
Abstract: Type IVa pili are ubiquitous and versatile bacterial cell surface filaments that undergo cycles of extension, adhesion and retraction powered by the cell-envelope spanning type IVa pilus machine (T4aPM). The overall architecture of the T4aPM…
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Keywords:
minor pilins;
type iva;
myxococcus xanthus;
iva pilus ... See more keywords
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Published in 2023 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnad007
Abstract: Polyphosphate kinase 1 (Ppk1) generates polyphosphates (polyPs) by catalyzing phosphate transfer from ATP. In the presence of ATP, Myxococcus xanthus Ppk1 showed the highest activity with polyP60-70 but also showed high activity with orthophosphate and…
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Keywords:
chain polyps;
polyphosphate;
myxococcus xanthus;
ppk1 ... See more keywords
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Published in 2018 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000152
Abstract: Predation is a fundamental ecological process, but within most microbial ecosystems the molecular mechanisms of predation remain poorly understood. We investigated transcriptome changes associated with the predation of Escherichia coli by the myxobacterium Myxococcus xanthus…
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Keywords:
changes myxococcus;
escherichia coli;
myxococcus xanthus;
predator ... See more keywords