Echocardiographic predictors of first onset of atrial fibrillation in dogs with myxomatous mitral valve disease
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DOI: 10.1111/jvim.15860
Abstract: Abstract Background Atrial fibrillation (AF) occurs in dogs with myxomatous mitral valve disease (MMVD) as a consequence of left atrial (LA) dilatation, and it affects survival and quality of life. Objectives To evaluate the usefulness… read more here.
Keywords: atrial fibrillation; mitral valve; dogs myxomatous; myxomatous mitral ... See more keywords
The Mitral INsufficiency Echocardiographic score: A severity classification of myxomatous mitral valve disease in dogs
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DOI: 10.1111/jvim.16131
Abstract: Abstract Background There is no commonly shared severity score for myxomatous mitral valve disease (MMVD) based on routinely acquired echocardiographic variables. Hypothesis/Objectives To propose an easy‐to‐use echocardiographic classification of severity of MMVD in dogs. Animals… read more here.
Keywords: classification; disease; mitral valve; severity ... See more keywords
Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of veterinary internal medicine"
DOI: 10.1111/jvim.16277
Abstract: BACKGROUND The neurotransmitter serotonin (5-HT) affects valvular degeneration and dogs with myxomatous mitral valve disease (MMVD) exhibit alterations in 5-HT signaling. In Maltese dogs, 3 single nucleotide polymorphisms (SNPs) in the 5-HT transporter (SERT) gene… read more here.
Keywords: mmvd; gene; myxomatous mitral; serum concentration ... See more keywords
Evaluation of urinary neutrophil gelatinase‐associated lipocalin to detect renal tubular damage in dogs with stable myxomatous mitral valve disease
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DOI: 10.1111/jvim.16503
Abstract: Abstract Background Dogs with myxomatous mitral valve disease (MMVD) can experience progressive renal tubular damage and dysfunction. The prevalence of renal tubular damage is not known in dogs with stable MMVD. Objective To evaluate renal… read more here.
Keywords: tubular damage; myxomatous mitral; damage; renal tubular ... See more keywords
Effect of atorvastatin on oxidative stress and inflammation markers in myxomatous mitral valve disease in dogs: A comparison of subclinical and clinical stages
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DOI: 10.1111/jvp.12746
Abstract: Myxomatous mitral valve disease (MMVD) is the most common acquired cardiac disorder found in dogs. The disease process can lead to heart failure (HF) and has been found to be associated with oxidative stress and… read more here.
Keywords: stress inflammation; mitral valve; stress; myxomatous mitral ... See more keywords
The chromogranin A-derived peptides catestatin and vasostatin in dogs with myxomatous mitral valve disease
Sign Up to like & getrecommendations! Published in 2020 at "Acta Veterinaria Scandinavica"
DOI: 10.1186/s13028-020-00541-3
Abstract: Background The protein chromogranin A (CgA) is stored and co-released with catecholamines from the stimulated adrenal glands. Increased plasma concentrations of CgA have been shown in people with heart disease. The aim of the study… read more here.
Keywords: peptides catestatin; plasma concentrations; disease; blood ... See more keywords
Key nutrients important in the management of canine myxomatous mitral valve disease and heart failure.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Veterinary Medical Association"
DOI: 10.2460/javma.22.07.0319
Abstract: The most common cause of heart failure in dogs is myxomatous mitral valve disease (MMVD), which accounts for approximately 75% of canine heart disease cases and is especially common in smaller dogs. Although low-sodium diets… read more here.
Keywords: heart failure; myxomatous mitral; disease; valve disease ... See more keywords
Short-Term Effects of Sacubitril/valsartan on Echocardiographic Parameters in Dogs With Symptomatic Myxomatous Mitral Valve Disease
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DOI: 10.3389/fvets.2021.700230
Abstract: Background and Objective: Sacubitril/valsartan (SV) is an angiotensin receptor-neprilysin inhibitor that works by inhibiting the neprilysin enzyme as well as blocking angiotensin receptors. The benefits of using SV in congestive heart failure patients has been… read more here.
Keywords: sacubitril valsartan; mitral valve; myxomatous mitral; short term ... See more keywords
Genetic Variants at the Nebulette Locus Are Associated with Myxomatous Mitral Valve Disease Severity in Cavalier King Charles Spaniels
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DOI: 10.3390/genes13122292
Abstract: The most common cardiovascular disease in domestic dogs is myxomatous mitral valve disease (MMVD), accounting for 75% of all cardiac disease. An increase in age is generally associated with increased incidence of the disease, but… read more here.
Keywords: myxomatous mitral; disease; valve disease; mitral valve ... See more keywords
Serum Proteomic Profiles Reflect the Stages of Myxomatous Mitral Valve Disease in Dogs
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DOI: 10.3390/ijms24087142
Abstract: Canine myxomatous mitral valve disease (MMVD) is similar to Barlow’s form of MMVD in humans. These valvulopathies are complex, with varying speeds of progression. We hypothesized that the relative abundances of serum proteins would help… read more here.
Keywords: mmvd; myxomatous mitral; disease; valve disease ... See more keywords
Prevalence of Reticulocytosis in the Absence of Anemia in Dogs with Cardiogenic Pulmonary Edema Due to Myxomatous Mitral Valve Disease: A Retrospective Study
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DOI: 10.3390/vetsci9060293
Abstract: Myxomatous mitral valve disease (MMVD) is the most common heart disease in small breed dogs. Dogs with MMVD commonly show clinical signs of dyspnea due to cardiogenic pulmonary edema (CPE). Reticulocytosis in the absence of… read more here.
Keywords: myxomatous mitral; disease; valve disease; mitral valve ... See more keywords