Articles with "n178t variant" as a keyword



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Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1049696

Abstract: Human P2Y4 is a UTP receptor, while in mice it is activated by both ATP and UTP. P2Y4 knockout (KO) in mice protects against myocardial infarction and is characterized by increased adiponectin secretion by adipocytes,… read more here.

Keywords: human p2y4; p2y4 receptor; p2y4; n178t variant ... See more keywords