Articles with "n58 glycosylation" as a keyword



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PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.826045

Abstract: Immune checkpoint therapy (ICT) with a monoclonal antibody (MAb) against programmed cell death protein 1 (PD-1) is a powerful clinical treatment for tumors. Cemiplimab is a human IgG4 antibody approved in 2018 and is the… read more here.

Keywords: immune checkpoint; n58 glycosylation; checkpoint therapy; glycosylation ... See more keywords