Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aax1595
Abstract: We demonstrate that the decrease in conformational stability underlies the oncogenic activity of the N92I mutant of Rac1. Ras-related C3 botulinum toxin substrate 1 (Rac1) functions as a molecular switch by cycling between an inactive… read more here.
Keywords: ras related; n92i mutant; mutant; conformational stability ... See more keywords