Simple synthesis of 3-hydroxyquinolines via Na2S2O4-mediated reductive cyclization of (2-(2-nitrophenyl)oxiran-1-yl)(aryl)methanones (o-nitrobenzalacetophenone oxides)
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DOI: 10.1016/j.tet.2017.06.058
Abstract: Abstract An efficient sodium dithionite (Na2S2O4)-mediated method for construction of 3-hydroxyquinolines via in situ Meinwald rearrangement/intramolecular reductive cyclization of o-nitrobenzalacetophenone oxides has been developed. The practical approach is of excellent functional group compatibility with as… read more here.
Keywords: na2s2o4 mediated; nitrobenzalacetophenone oxides; hydroxyquinolines via; reductive cyclization ... See more keywords