The impact of histopathology and NAB2–STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neuropathologica"
DOI: 10.1007/s00401-018-1952-6
Abstract: Meningeal solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is a rare tumor with propensity for recurrence and metastasis. Although multiple classification schemes have been proposed, optimal risk stratification remains unclear, and the prognostic impact of fusion status… read more here.
Keywords: recurrence; histopathology; stat6 fusion; nab2 stat6 ... See more keywords
NAB2-STAT6 fusion protein mediates cell proliferation and oncogenic progression via EGR-1 regulation.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.090
Abstract: Solitary fibrous tumors are rare mesenchymal tumors derived from soft tissues and vascular walls. NAB2-STAT6 fusion gene serves as a marker gene for this disease and consists of the truncated repressor domain of NGFI-A-Binding protein… read more here.
Keywords: cell proliferation; oncogenic progression; proliferation; stat6 fusion ... See more keywords
A rare case of a solitary fibrous tumour of bone showing NAB2–STAT6 exon 3–exon 19 fusion
Sign Up to like & getrecommendations! Published in 2018 at "Histopathology"
DOI: 10.1111/his.13658
Abstract: a solitary fibrous tumour (SFT) is a mesenchymal tumour of fibroblastic origin that invariably displays a prominent hemangiopericytoma (HPC)-like vasculature. Currently, hemangiopericytoma (HPC) of soft tissues is a disregarded entity and is rather considered as… read more here.
Keywords: solitary fibrous; fibrous tumour; fusion; nab2 stat6 ... See more keywords
Pancreatic hamartoma: detection of harbouring NAB2::STAT6 fusion gene
Sign Up to like & getrecommendations! Published in 2022 at "Histopathology"
DOI: 10.1111/his.14703
Abstract: Hamartomas in the pancreas are rare and are often histologically and morphologically similar to solitary fibrous tumours (SFTs). We examined the differences between hamartomas and SFTs at the molecular level. read more here.
Keywords: pancreatic hamartoma; nab2 stat6; harbouring nab2; hamartoma detection ... See more keywords