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A Capped Peptide of the Aggregation Prone NAC 71–82 Amino Acid Stretch of α-Synuclein Folds into Soluble β-Sheet Oligomers at Low and Elevated Peptide Concentrations

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21051629

Abstract: Although Lewy bodies and Lewy neurites are hallmarks of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), misfolded α-synuclein oligomers are nowadays believed to be key for the development of these diseases. Attempts to… read more here.

Keywords: capped peptide; aggregation prone; aggregation; nac amino ... See more keywords