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The T1‐tetramerisation domain of Kv1.2 rescues expression and preserves function of a truncated NaChBac sodium channel

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Published in 2022 at "Febs Letters"

DOI: 10.1002/1873-3468.14279

Abstract: Cytoplasmic domains frequently promote functional assembly of multimeric ion channels. To investigate structural determinants of this process, we generated the ‘T1‐chimera’ construct of the NaChBac sodium channel by truncating its C‐terminal domain and splicing the… read more here.

Keywords: nachbac sodium; sodium channel; domain; channel ... See more keywords