Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3748
Abstract: Glutamate dehydrogenase (GDH) is a target for treating insulin‐related disorders, such as hyperinsulinism hyperammonemia syndrome. Modeling native ligand binding has shown promise in designing GDH inhibitors and activators. Our computational investigation of the nicotinamide adenine… read more here.
Keywords: binding; nadh adp; site; glutamate dehydrogenase ... See more keywords