Radiodegradation of nadolol in the solid state and identification of its radiolysis products by UHPLC–MS method
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DOI: 10.1007/s11696-017-0284-7
Abstract: Nadolol ((2R*,3S*)-5-{[(2R*)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-1,2,3,4 tetrahydronaphthalene-2,3-diol) in substantia was exposed to ionizing radiation generated by a beam of high-energy electrons in an accelerator, in the standard sterilisation dose of 25 kGy and in higher doses of 50 − 400 kGy. The irradiated… read more here.
Keywords: solid state; nadolol solid; radiolysis products; radiodegradation nadolol ... See more keywords