Improving isobutanol titers in Saccharomyces cerevisiae with over-expressing NADPH-specific glucose-6-phosphate dehydrogenase (Zwf1)
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Microbiology"
DOI: 10.1007/s13213-017-1304-0
Abstract: Isobutanol is a more promising biofuel than ethanol due to its higher energy density and lower hygroscopicity. Saccharomyces cerevisiae, as a model eukaryote, has the potential advantage to produce isobutanol because of its greater tolerance… read more here.
Keywords: saccharomyces cerevisiae; isobutanol titers; phosphate dehydrogenase; glucose phosphate ... See more keywords
Simulations of Shikimate Dehydrogenase from Mycobacterium tuberculosis in Complex with 3-Dehydroshikimate and NADPH Suggest Strategies for MtbSDH Inhibition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00834
Abstract: Shikimate dehydrogenase (SDH) from Mycobacterium tuberculosis ( MtbSDH), encoded by the aroE gene, is essential for viability of M. tuberculosis but absent from humans. Therefore, it is a potentially promising target for antituberculosis agent development.… read more here.
Keywords: shikimate dehydrogenase; nadph; mtbsdh; nadph binding ... See more keywords
NADPH is superior to NADH or edaravone in ameliorating metabolic disturbance and brain injury in ischemic stroke.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-021-00705-5
Abstract: Our previous studies confirm that exogenous reduced nicotinamide adenine dinucleotide phosphate (NADPH) exerts a neuroprotective effect in animal models of ischemic stroke, and its primary mechanism is related to anti-oxidative stress and improved energy metabolism.… read more here.
Keywords: nadph; superior nadh; nadh edaravone; ischemic stroke ... See more keywords