Co-expression of an alcohol dehydrogenase and a cyclohexanone monooxygenase for cascade reactions facilitates the regeneration of the NADPH cofactor.
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DOI: 10.1016/j.enzmictec.2017.09.003
Abstract: The introduction of a three-enzyme cascade (comprising a cyclohexanone monooxygenase (CHMO), an alcohol dehydrogenase (ADH) and a lipase (CAL-A)) for the production of oligo-ε-caprolactone provided self-sufficiency with respect to NADPH-cofactor regeneration and reduced inhibiting effects… read more here.
Keywords: cyclohexanone monooxygenase; regeneration; expression; alcohol dehydrogenase ... See more keywords